Electrophilic γ-Lactone κ-Opioid Receptor Probes. Analogues of 2'-Hydroxy-2-tetrahydrofurfuryl-5,9-dimethyl-6,7-benzomorphan Diastereomers

DOI: 10.1021/jm00112a019

Source and publish data:

Journal of Medicinal Chemistry p. 2438 - 2444 (1991)

Update date:2022-09-26

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Authors:

Klein, Peter

Nelson, Wendel L.

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Article abstract of DOI:10.1021/jm00112a019

Benzomorphans with an electrophilic group in the nitrogen substituent were prepared as potentially irreversible ligands for the κ-opioid receptor.These were synthesized from products of the reaction of normetazocine with the enantiomers of 5-(iodomethyl)-

Full text of DOI:10.1021/jm00112a019

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