Development, Synthesis, and Biological Evaluation of (-)-trans-(2S,5S)-2--4-n-propoxy-5-(3-hydroxypropoxy)-phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a Potent Orally Active Platelet-Activating Factor (PAF) Antagonist and

DOI: 10.1021/jm00097a005

Source and publish data:

Journal of Medicinal Chemistry p. 3474 - 3482 (1992)

Update date:2022-08-02

Topics:

Authors:

Girotra, N. N.

Biftu, T.

Ponpipom, M. M.

Acton, J. J.

Alberts, A. W.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00097a005

(-)-trans-(2S,5S)-2-<3-<(2-Oxopropyl)sulfonyl>-4-n-propoxy-5-(3-hydroxypropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (10) is one of the most potent platelet-activating factor (PAF) antagonists in vitro and in vivo developed to date.This diaryl

Full text of DOI:10.1021/jm00097a005

Products guided by the article

Product name:3-bromopropyl dibenzyl phosphate

Cas No:134169-26-9

R&D Labs maybe for 134169-26-9

Shanghai Maxchemco Chemical Industry Co., Ltd.

Contact:(86)21-51079223

Address:No.1305-8, B241, the Ecust Park, Huajing Road, Xuhui District, Shanghai
Xian Changyue Biological Technology Co., Ltd.

website:https://www.xachangyue.com/

Contact:+86-029-88211911

Address:Keji Road NO.70
Wuxi Zuping Food Science And Technology Co.,LTD.

Contact:+86-510-87210822

Address:Guanlin town
TC CHEMICALS CO.,LTD

Contact:0550-7041128 0550-7090578

Address:Wangdian Street,Xinjie Town
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.

Contact:+86-512-6585 6968

Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China

Relevant to this article

Axial donating ligands: A new strategy for late transition metal olefin polymerization catalysis

Doi:10.1021/ja8017847
(2008)
Pyrrolo-dC oligonucleotides bearing alkynyl side chains with terminal triple bonds: Synthesis, base pairing and fluorescent dye conjugates prepared by the azide-alkyne click reaction

Doi:10.1039/b719459e
(2008)
Synthesis, Structure-Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT₄ Receptor Partial Agonists

Doi:10.1021/acs.jmedchem.8b00457
(2018)
Doi:10.1021/jo01017a533
(1965)
Luminescence quenching in supramolecular assemblies of quantum dots and bipyridinium dications

Doi:10.1039/b720038b
(2008)
Doi:10.1021/jo01093a617
(1959)

Article Doi