1,4:3,6-Dianhydrohexitol nitrate derivatives. I. Synthesis and antianginal activity of alkylpiperazine derivatives

DOI: 10.1248/cpb.41.1091

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1091 - 1099 (1993)

Update date:2022-07-30

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Authors:

Hayashi Hayashi

Ikeda Ikeda

Kuroda Kuroda

Kubo Kubo

Sano Sano

Suzuki Suzuki

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Article abstract of DOI:10.1248/cpb.41.1091

A series of 5-deoxy-5-(4-substituted piperazin-1-yl)-1,4:3,6-dianhydro-L- iditol 2-nitrates was prepared and evaluated for oral anti-ischemic activities. Inhibition of lysine-vasopressin-induced T-wave elevation in the electrocardiogram (ECG) of rats (ang

Full text of DOI:10.1248/cpb.41.1091

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