A new highly diastereoselective synthesis of 2,5-disubstituted-1,3-dioxolan-4-ones from α-hydroxyacids

DOI: 10.1016/0040-4039(91)80352-7

Source and publish data:

Tetrahedron Letters p. 1441 - 1442 (1991)

Update date:2022-09-26

Topics:

Authors:

Chapel Chapel

Greiner Greiner

Ortholand

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Article abstract of DOI:10.1016/0040-4039(91)80352-7

Reaction of α-hydroxyacids with acetals under weak acid catalysis gave the corresponding dioxolanones with a better diastereomeric ratio than the usual strong acid catalyzed synthesis from aldehydes.

Full text of DOI:10.1016/0040-4039(91)80352-7

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