Enantioselective Total Synthesis of Indolizidine Alkaloids (-)-205A and (-)-235B

DOI: 10.1021/jo00016a013

Source and publish data:

Journal of Organic Chemistry p. 4868 - 4874 (1991)

Update date:2022-08-05

Topics:

Authors:

Polniaszek, Richard P.

Belmont, Stephen E.

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Article abstract of DOI:10.1021/jo00016a013

Enantioselective total syntheses of indolizidine alkaloids (-)-205A and (-)-235B are described.The syntheses proceed via a common late-stage intermediate, α-aminonitrile 1.Absolute stereochemical control over the C8 and C8a stereocenters in these material

Full text of DOI:10.1021/jo00016a013

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