Synthesis of thienopyridines and isoquinolines from 6-amino-1,2-dihydro-4-methyl-2-thioxopyridine-3,5-dicarbonitrile and of phthalazines from thieno[3,4-c]pyridazines

Article abstract of DOI:10.3797/scipharm.aut-00-36

Thienopyridine 1 and thienopyridazine 13 have been readily reacted with electron-poor olefins to give isoquinolines and phthalazines, respectively. Some of the obtained compounds were tested for their antimicrobial activity.