Nucleophilic Ring-Opening of Chlorooxiranes: A New Synthesis of α-Hydroxy α'-Substituted Ketones from Carbonyl Compounds and 1-Chloroalkyl p-Tolyl Sulfoxides

DOI: 10.1246/bcsj.64.1582

Source and publish data:

Bulletin of the Chemical Society of Japan p. 1582 - 1587 (1991)

Update date:2022-08-05

Topics: Carbonyl Compounds

Authors:

Satoh, Tsuyoshi

Ogura, Asako

Ikeda, Youko

Yamakawa, Koji

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Article abstract of DOI:10.1246/bcsj.64.1582

The addition of 1-chloroalkyl p-tolyl sulfoxides to carbonyl compounds gave adducts which were then converted to chlorooxiranes in two steps with good overall yields.The treatment of the chlorooxiranes with various nucleophiles gave α-hydroxy α'-substitut

Full text of DOI:10.1246/bcsj.64.1582

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