A modular approach to trim cellular targets in anticancer drug discovery

DOI: 10.1016/j.bmcl.2011.09.069

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 6641 - 6645 (2011)

Update date:2022-08-05

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Authors:

Ríos-Luci, Carla

Domínguez-Kelly, Raquel

León, Leticia G.

Díaz-Rodríguez, Elena

Freire, Raimundo

Pandiella, Atanasio

Cikotiene, Inga

Padrón, José M.

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Article abstract of DOI:10.1016/j.bmcl.2011.09.069

A Phenotypic Drug Discovery strategy was applied to study a set of pyrimidine analogs prepared by means of intramolecular oxidation-reduction reactions of N-substituted-N-(2,6-disubstituted-5-nitro-4-pyrimidinyl) aminoacetic acid methyl esters in basic me

Full text of DOI:10.1016/j.bmcl.2011.09.069

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