Bulletin of the Chemical Society of Japan p. 1041 - 1046 (1992)
Update date:2022-08-06
Topics:
Sunamoto, Junzo
Akiyoshi, Kazunari
Kihara, Tetsuji
Endo, Masayuki
A water-soluble spin probe, disodium 4-<(4,8-sulfonatooxy-2-naphthyl)thioureylene>-2,2,6,6-tetramethyl-1-piperidinyloxyl (TEMPO-T) was newly synthesized and characterized comparing with several defferent TEMPO derivatives from the view point of a possibility of utilization in the liposomal studies.Of TEMPO derivatives studied, TEMPO-T was the best probe because of the high water solubility, the less lipophilicity, the less leakiness from liposome, and the reliable stability to both temperature and pH changes.
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