Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 107868 > 

107868-30-4

Basic Information
CAS No.: 107868-30-4
Name: 6-Methyleneandrosta-1,4-diene-3,17-dione
Molecular Structure:
Molecular Structure of 107868-30-4 (6-Methyleneandrosta-1,4-diene-3,17-dione)
Formula: C20H24O2
Molecular Weight: 296.41
Synonyms: Exemestane [USAN:INN:BAN];Aromasil;Aromasin;FCE 24304;Exemestane Tablets;Androsta-1,4-diene-3,17-dione, 6-methylene-;Exemestano;Exemestano [INN-Spanish];Exemestanum;Exemestanum [INN-Latin];HSDB 7463;Exemestane;
EINECS: 643-090-2
Density: 1.13 g/cm3
Melting Point: 155.13 ºC
Boiling Point: 453.7 ºC at 760 mmHg
Flash Point: 169 ºC
Solubility:
Appearance: white to light yellow crystal powder
Hazard Symbols: T,N
Risk Codes: 60-61-51
Safety: 53-22-36/37-57
Transport Information:
PSA: 34.14000
LogP: 4.02950
Synthetic route
122370-91-6

17β-hydroxy-6-methylen- androsta-1,4-dien-3-one

107868-30-4

exemestane

Conditions
ConditionsYield
With Jones reagent In acetone at -20℃; Jones oxidation; Inert atmosphere;100%
With jones reagent In acetone at -20℃; for 0.25h;85%
With Jones reagent In acetone at 0℃; Product distribution / selectivity;
933455-74-4

6α-hydroxymethylandrosta-1,4-diene-3,17-dione

107868-30-4

exemestane

Conditions
ConditionsYield
Stage #1: 6α-hydroxymethylandrosta-1,4-diene-3,17-dione With methanesulfonyl chloride; triethylamine In dichloromethane at 0 - 30℃;
Stage #2: With methanol; potassium hydroxide at 40 - 50℃;
90%

17-hydroxyimino-6-methylenandrosta-1,4-diene-3-one

107868-30-4

exemestane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In water; acetone at 25 - 30℃; for 10h; Solvent; Reagent/catalyst; Temperature; Jones Oxidation; Inert atmosphere;88.2%
19457-55-7

6-methylene-androst-4-ene 3,17-dione

107868-30-4

exemestane

Conditions
ConditionsYield
With N,O-Bis(trimethylsilyl)trifluoroacetamide; chloranil; trifluorormethanesulfonic acid In toluene at 108 - 110℃; for 0.75h; Product distribution / selectivity; Heating / reflux;81.8%
With trifluorormethanesulfonic acid; N,O-Bis(trimethylsilyl)trifluoroacetamide; chloranil In toluene Inert atmosphere; Reflux;81%
With tert-butyldimethylsilyl chloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane at 0 - 20℃;30.2%
67-56-1

methanol

121021-51-0

6β-hydroxymethylandrosta-1,4-diene-3,17-dione

A

(6S,8R,9S,10R,13S,14S)-6-(methoxymethyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione

B

107868-30-4

exemestane

Conditions
ConditionsYield
With hydrogenchloride at 20℃; for 24h;A 8%
B 60%
19457-55-7, 51154-17-7

6-Methylen-4-androsten-3,17-dion

107868-30-4

exemestane

Conditions
ConditionsYield
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide; toluene at 85℃; for 48h; Inert atmosphere; Large scale;56.7%
897-06-3

Androsta-1,4-diene-3,17-dione

107868-30-4

exemestane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 20 h / Heating
2: 1.10 g / benzene; ethanol; H2O / 5 h / 20 °C
3: 60 percent / conc. HCl / 24 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1.1: hydroxylamine hydrochloride; sodium acetate / water; ethanol / 6 h / Inert atmosphere; Reflux
2.1: N,N-dimethylammonium chloride / i-Amyl alcohol / 2 h / Inert atmosphere; Reflux
2.2: 15 h / 140 °C
3.1: toluene-4-sulfonic acid / water; acetone / 10 h / 25 - 30 °C / Inert atmosphere
View Scheme
Multi-step reaction with 4 steps
1: orthoformic acid triethyl ester; toluene-4-sulfonic acid / tetrahydrofuran / 12 h / 40 - 45 °C / Large scale
2: tetrahydrofuran; ethanol / 10 h / 40 - 45 °C / Large scale
3: hydrogenchloride / tetrahydrofuran; ethanol / 1 h / Large scale
4: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide; toluene / 48 h / 85 °C / Inert atmosphere; Large scale
View Scheme
67737-88-6

1α,3-dipyrrolidinylandrosta-3,5-dien-17-one

107868-30-4

exemestane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.10 g / benzene; ethanol; H2O / 5 h / 20 °C
2: 60 percent / conc. HCl / 24 h / 20 °C
View Scheme
846-48-0

1-dehydrotestosterone

107868-30-4

exemestane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) Me2NH*HCl / 1.) isoamyl alcohol, reflux, 2 h, 2.) isoamyl alcohol, reflux, 15 h
2: 85 percent / Jones reagent / acetone / 0.25 h / -20 °C
View Scheme
861395-77-9

C21H28O5S

107868-30-4

exemestane

Conditions
ConditionsYield
With potassium hydroxide In methanol; dichloromethane; water at 25℃; Heating / reflux;
7440-44-0

pyrographite

19457-55-7

6-methylene-androst-4-ene 3,17-dione

75-65-0

tert-butyl alcohol

107868-30-4

exemestane

Conditions
ConditionsYield
With selenium(IV) oxide In ethyl acetate

6-hydroxymethyl-androsta-1,4-diene-3,17-dione

107868-30-4

exemestane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 80 - 90℃; under 315 Torr; for 4h; Purification / work up;
With toluene-4-sulfonic acid In toluene at 90℃; for 3h; Purification / work up;
With camphor-10-sulfonic acid In toluene at 90℃; for 7h; Purification / work up;
With (1S)-10-camphorsulfonic acid In ethyl acetate at 70 - 80℃; for 32h; Purification / work up;
Stage #1: 6-hydroxymethyl-androsta-1,4-diene-3,17-dione With pyridine; p-toluenesulfonyl chloride at 0℃; for 48h;
Stage #2: With potassium hydroxide In methanol; water at 65℃; for 2h; Purification / work up;
53-43-0

dehydroepiandrosterone

107868-30-4

exemestane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: toluene / 1 h / 120 °C / Inert atmosphere
1.2: 0.33 h / 20 °C / Inert atmosphere
1.3: 3 h / 20 °C / Inert atmosphere
2.1: orthoformic acid triethyl ester; toluene-4-sulfonic acid / ethanol; tetrahydrofuran / 3 h / 40 °C
2.2: 4 h / 40 °C
3.1: Arthrobacter simplex ATCC6946 culture / aq. buffer / 33 °C / Microbiological reaction
View Scheme
972-46-3

3-Aethoxy-androstadien-(3,5)-on-(17)

107868-30-4

exemestane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetrahydrofuran; ethanol / 10 h / 40 - 45 °C / Large scale
2: hydrogenchloride / tetrahydrofuran; ethanol / 1 h / Large scale
3: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide; toluene / 48 h / 85 °C / Inert atmosphere; Large scale
View Scheme

6-methyleneandrostenediol ketal

107868-30-4

exemestane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In tetrahydrofuran; water at 20 - 25℃; for 10h; Inert atmosphere;
107868-30-4

exemestane

184972-12-1

FCE27353

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 48h; Ambient temperature;80%
107868-30-4

exemestane

C20H24N6O2

Conditions
ConditionsYield
With copper(l) iodide; tert-Butyl peroxybenzoate; trimethylsilylazide In acetonitrile at 50℃; for 6h; Reagent/catalyst; Solvent; Schlenk technique; Inert atmosphere; Green chemistry;75%
107868-30-4

exemestane

A

2241-94-3

6α-methylandrost-4-ene-3,17-dione

B

C20H30O2

C

5696-36-6

6β-methylandrost-4-ene-3,17-dione

Conditions
ConditionsYield
With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 5%-palladium/activated carbon In ethanol for 18h; Reflux; stereoselective reaction;A n/a
B 62%
C n/a
50-00-0

formaldehyd

107868-30-4

exemestane

C21H24O2

Conditions
ConditionsYield
With N,N-dimethylammonium chloride In ethanol at 78℃; for 3h; Temperature; Mannich Aminomethylation;54.1%
349-88-2

4-Fluorobenzenesulfonyl chloride

107868-30-4

exemestane

(6S,8R,9S,10R,13S,14S)-6-(((4-fluorophenyl)sulfonyl)methyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione

Conditions
ConditionsYield
With fac-tris(2-phenylpyridinato-N,C2')iridium(III); tris-(trimethylsilyl)silane In acetonitrile at 20℃; for 16h; Irradiation; diastereoselective reaction;50%
107868-30-4

exemestane

A

6-methylandrosta-1,4,6-trien-17β-ol

B

122370-91-6

17β-hydroxy-6-methylen- androsta-1,4-dien-3-one

Conditions
ConditionsYield
With sodium tetrahydroborate; acetic acid; trifluoroacetic acid In dichloromethane; acetonitrile at 20℃; for 11h; Inert atmosphere;A 11.3 mg
B 39%
75-63-8

Bromotrifluoromethane

107868-30-4

exemestane

A

C21H25F3O3

B

C21H25F3O3

Conditions
ConditionsYield
With cobalt(II) tetrafluoroborate hexahydrate; N-isopropyl-N,2-dimethylpropan-2-amine In water; N,N-dimethyl-formamide; acetonitrile at 65℃; for 24h; Sealed tube;A 30%
B 33%
75-63-8

Bromotrifluoromethane

107868-30-4

exemestane

A

C21H25F3O3

B

C21H25F3O3

Conditions
ConditionsYield
With cobalt(II) tetrafluoroborate hexahydrate; N-isopropyl-N,2-dimethylpropan-2-amine In N,N-dimethyl-formamide; acetonitrile at 65℃; for 24h;A 30%
B 33%
75-52-5

nitromethane

107868-30-4

exemestane

911856-13-8

6α-(2-Nitroethyl)androsta-1,4-dien-3,17-dion

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 22h; Michael addition; Heating;32%
107868-30-4

exemestane

A

6α-spirooxiranandrosta-1,4-diene-3,17-dione

B

6α-spirooxiranandrosta-1,4-diene-3,17-dione

Conditions
ConditionsYield
With formic acid; dihydrogen peroxide In dichloromethane at 20℃; for 96h;A 21%
B 76.1 mg
52-90-4

L-Cysteine

107868-30-4

exemestane

6-methylcysteinylandrosta-1,4-diene-3,17-dione

Conditions
ConditionsYield
With potassium hydroxide In methanol at 20℃; for 24h; Inert atmosphere;13%
107868-30-4

exemestane

1α,2α-epoxy-6-methylenandrost-4-ene-3,17-dione

Conditions
ConditionsYield
With dihydrogen peroxide; sodium hydroxide In methanol; water at 0 - 20℃; for 24.5h;11%
107868-30-4

exemestane

105-53-3

diethyl malonate

Diethyl-2-(3,17-dioxoandrosta-1,4-dien-6β-ylmethyl)-malonat

Conditions
ConditionsYield
With sodium In ethanol for 7h; Michael addition; Heating;6%
107868-30-4

exemestane

911856-14-9

6α-(2-Oxoethyl)androsta-1,4-dien-3,17-dion

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 32 percent / NaOEt / ethanol / 22 h / Heating
2.1: KOH / methanol / 3 h / 20 °C
2.2: 31 percent / aq. H2SO4 / methanol / 4 h / cooling
View Scheme
107868-30-4

exemestane

Dimethyl-4-[(3,17-dioxoandrosta-1,4-dien-6α-yl)methyl]-2,6-dimethyl-3,5-pyridindicarboxylat

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 32 percent / NaOEt / ethanol / 22 h / Heating
2.1: KOH / methanol / 3 h / 20 °C
2.2: 31 percent / aq. H2SO4 / methanol / 4 h / cooling
3.1: 58 percent / acetic acid / 22 h / 20 - 60 °C
4.1: 87 percent / CAN / acetone; H2O / 0.5 h
View Scheme
107868-30-4

exemestane

911856-15-0

Dimethyl-4-[(3,17-dioxoandrosta-1,4-dien-6α-yl)methyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridindicarboxylat

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 32 percent / NaOEt / ethanol / 22 h / Heating
2.1: KOH / methanol / 3 h / 20 °C
2.2: 31 percent / aq. H2SO4 / methanol / 4 h / cooling
3.1: 58 percent / acetic acid / 22 h / 20 - 60 °C
View Scheme
107868-30-4

exemestane

6-Hydroxymethylexemestane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / 50percent m-chloroperbenzoic acid / CH2Cl2 / 48 h / Ambient temperature
2: 38 percent / 20percent aq. HClO4 / tetrahydrofuran / 3 h / Ambient temperature
View Scheme
107868-30-4

exemestane

6α/β-hydroxy-6α/β-hydroxymethylandrosta-1,4-diene-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / 50percent m-chloroperbenzoic acid / CH2Cl2 / 48 h / Ambient temperature
2: 42 percent / 20percent aq. HClO4 / tetrahydrofuran / 3 h / Ambient temperature
View Scheme
  • Display:default sort

    New supplier

  • Exemestane Manufacturer/High quality/Best price/In stock

  • Casno:

    107868-30-4

    Exemestane Manufacturer/High quality/Best price/In stock

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Why choice me: √1, We guarantee deeply analyze and demonstrate, purity more than 99% √ 2, Factory outlet with priority price & large stock. √ 3, Special magic vacuum safe package & safe shipping way.All parcel shipme

    Zibo Dorne chemical technology co., LTD. Is a comprehensive chemical enterprise integrating r&d, production and sales. It is a leading manufacturer and supplier of chemical product

  •  Zibo Dorne chemical technology co. LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-533-2362027

    Address:No. 416, 4th floor, zhongguancun science and technology city, no. 1, west 6th road, zhangdian district

       Inquiry Now

  • Exemestane/Aromasin Anti Estrogen Steroids Powder An antineoplastic

  • Casno:

    107868-30-4

    Exemestane/Aromasin Anti Estrogen Steroids Powder An antineoplastic

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Rich experience. We have specialized in this field for 7 years. Our steroids and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. And we have got very good feedback from our customers, and establ

    Hubei God bull Pharmaceutical Co.,Ltd is a leading pharmaceutical and plant extract factory which is special in steroid powder and pahrmaceutical intermediate,plant extract. .Acco

  •  Hubei God bull Pharmaceutical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:15926470212

    Address:No.58, guanggu avenue, east lake new technology development zone, wuhan

       Inquiry Now

  • good supplier Exemestane in Chinahigh purity 107868-30-4

  • Casno:

    107868-30-4

    good supplier Exemestane in Chinahigh purity 107868-30-4

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 10.0-30.0/Kilogram

    Hebei Huanhao Biotechnology co., Ltd. is one of the most dynamic research and advanced technology companies. We can serve well quality product and the way of our traffic is safty and efficently. For medical raw materials , for

    Hebei Yingong New Material Technology Co.,Ltd is one of the most dynamic research and advanced technology companies.We now have the most complete range of pharmaceutical intermedia

  •  Hebei Yingong New Material Technology Co.,Ltd .

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18034554576

    Address:Shijiazhuang

       Inquiry Now

  • Exemestane manufacturer 99%

  • Casno:

    107868-30-4

    Exemestane manufacturer 99%

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    We are very strong on this product. Package:25kgs net carton drums Application:API Port:SHANGHAI

    CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD., founded in 1984, engages in pharmaceutical research, development, production, process design and technical consultation of syn

  •  CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-519-88802789

    Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China

       Inquiry Now

  • Exemestane( Aromasin) cas: 107868-30-4

  • Casno:

    107868-30-4

    Exemestane( Aromasin) cas: 107868-30-4

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    ProName: Exemestane( Aromasin) CasNo: 107868-30-4 Appearance: white powder Application: hormone therapy drug Purity: 99% Residue on Ignition: <1% Related Substances: Pharmaceutical grade Heavy Metal: 0% Appearance:white powder Stor

    ZHEJIANG BIOLOGY AND TECHNOLOGY CO., LTD. is a modern professional high-tech enterprise, which is specializing in generic APIs and pharmaceutical intermediates. especially in pepti

  •  Zhejiang J&C Biological Technology Co.,Limited

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:0570-4045877

    Address:46# zhongshan road, quzhou zhejiang

       Inquiry Now

  • Exemestane

  • Casno:

    107868-30-4

    Exemestane

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    We have strong R&D center which can support and provide custom synthesis accordingly such as fine chemicals,biotechnique , pharmaceuticals etc.We can provide free sample for our clients to test anf verify the quality of our goods.LongyuChem holds str

    Shanghai Longyu biotech Co., Ltd. is a large-scale modern chemical production enterprise dedicated to the production, research and development and sales of chemical products. It co

  •  shanghai Longyu biotechnology Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15821988213

    Address:Dalian Rd 950th

       Inquiry Now

  • Female Glucocorticoid Steroids Anti Estrogen Exemestane Aromasin Aromatase 107868-30-4

  • Casno:

    107868-30-4

    Female Glucocorticoid Steroids Anti Estrogen Exemestane Aromasin Aromatase 107868-30-4

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White powder Storage:Store in sealed containers at cool & dr

    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

  •  Hubei XinRunde Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+8618874586545

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

       Inquiry Now

  • Exemestane(Aromasin) CAS NO.107868-30-4 Factory High Quality

  • Casno:

    107868-30-4

    Exemestane(Aromasin) CAS NO.107868-30-4 Factory High Quality

    Min.Order: 1 Gram

    FOB Price:  USD $ 10.0-10.0/Gram

    High purity with HPLC & NMR chart 99% purity with low price in stock specilized in hard-to-find chemicals Indapamide CAS NO.26807-65-8 99% in stock Appearance:white powder Storage:keep away from heat,sparks and flames Package:1 gram/bag App

    Tianyuan pharmaceutical company in Zhangjiang Eastern has built 500 square meters of pilot laboratories, equipped with two sets of 50L glass reactor, four sets of 100L double react

  •  Shenzhen Tianyuan Pharmaceutical Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-755-23284190

    Address:B302,2 unit, Jin Lian Building, No. 134 Qianjin 2 Road, Taoyuan village, Xixiang Street, Baoan,Shenzhen,China

       Inquiry Now

  • ExemestaneCAS No.: 107868-30-4

  • Casno:

    107868-30-4

    ExemestaneCAS No.: 107868-30-4

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Wuhan Chen Chu Pharmaceutical Co., Ltd. was founded in 2009, the factory is located in Huangmei County, Huanggang City, Hubei Province, Longgan Lake Industrial Park, the sales department is located in Wuhan Hill Street SBI venture street off road,

    inan Baozhao Pharmaceutical Technology Co.,Ltd. specializing in pharmaceutical raw materials, intermediates and chemical products ,is a high-tech pharmaceutical enterprise . Ou

  •  Jinan Baozhao Pharmaceutical Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:0086-531-86397156 82371858 82371868

    Address:Huaneng Road, Jinan, Shandong ,China

       Inquiry Now

  • Exemestane 99% USP

  • Casno:

    107868-30-4

    MSDS/COA Download

    Exemestane 99% USP

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    We have GMP.it conforms to USP pending. Appearance:White crystalline powder Storage:room temperature Package:1kg/bag or customer requirements Application:used to treat breast cancer. Transportation:BY SEA AIR EXPRESS(EMS DHL FEDEX TNT) Port:Hangzho

    Dawn Ray is a R&D and process improvement company,which is located in Hangzhou,Zhejiang province,China. We are dealing in muti-application of pharmaceuticals(APIS),antiobics,food a

  •  Hangzhou Dawn Ray Pharmaceutical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-571-85335020

    Address:1018 Guangyin Building,No.42 E.Fengqi Road,Hangzhou,310012 China

       Inquiry Now

  • Exemestane

  • Casno:

    107868-30-4

    Exemestane

    Min.Order: 20 Milligram

    FOB Price:  USD $ 0.0-0.0/Milligram

    Shaanxi Cuicheng Biomedical Technology Co., Ltd. is located in Chuangzhi Industrial Park, Economic and Technological Development Zone, Hanzhong City, Shaanxi Province, China. It is a company specializing in natural medicines and high-throughput sc

    Shaanxi Cuicheng Biomedical Technology Co., Ltd. was established in April 2019 with a registered capital of 8 million RMB and is located in Chuangzhi Industrial Park, Economic and

  •  Shaanxi Cuicheng Biomedical Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:18791163155

    Address:economic development Zone

       Inquiry Now

  • Exemestane 107868-30-4 GMP manufacturer,Jiangsu Grand Xinyi

  • Casno:

    107868-30-4

    Exemestane 107868-30-4 GMP manufacturer,Jiangsu Grand Xinyi

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-1.0/Kilogram

    Exemestane 107868-30-4 GMP manufacturer,Jiangsu Grand Xinyi With annual turnover of more than USD15 million, Jiangsu Grand Xinyi Pharmaceutial Co.,Ltd (the predecessor is Yancheng Xinyi Pharm & Chem Co.,Ltd.).is a professional manufacturer of

    Jiangsu Grand Xinyi Pharmaceutial Co.,Ltd (the predecessor is Yancheng Xinyi Pharm & Chem Co.,Ltd.).is a professional manufacturer of hormones and steroids. It was established in 2

  •  JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-515-84383317

    Address:Chenli Road,Costal Chemical Area Binhai,Yancheng, Jiangsu,China

       Inquiry Now

  • Exemestane

  • Casno:

    107868-30-4

    Exemestane

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 50.0-100.0/Kilogram

    Certification: ISO, BRC, KOSHER, HALAL Application: meidicine addictive Type: extract Appearance: white Powder Part Used: shrimp shell

    Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries. Annually, mo

  •  Kono Chem Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-29-86107037-8015

    Address:No.11 Daqing Road,Lianhu District,Xi’an 710082,China

       Inquiry Now

  • High quality Exemestone supplier in China

  • Casno:

    107868-30-4

    High quality Exemestone supplier in China

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0/Metric Ton

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional

  •  Simagchem Corporation

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-592-2680277

    Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China

       Inquiry Now

  • Exemestane CAS:107868-30-4 Safe delivery Free of customs clearance

  • Casno:

    107868-30-4

    MSDS/COA Download

    Exemestane CAS:107868-30-4 Safe delivery Free of customs clearance

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-10.0/Kilogram

    What's our company advantages 1. Government support guarantees good company credibility and finance safe. 2. Finer chem is confident at the quality of the products, and would like to supply free sample to our customers. 3. Factory locates in n

    Mulei (Wuhan) New Material Technology Co. Ltd is a scientific and technological company integrating product research and development, manufacture and trading of chemical intermedia

  •  WUHAN MULEI NEW MATERIAL CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619831967063

    Address:Office1201#, Block C, Hanjie Headquarters International Plaza, Zhongbei Rd, Wuchang District, Wuhan

       Inquiry Now

  • CHemwill --   Exemestane

  • Casno:

    107868-30-4

    CHemwill -- Exemestane

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 1.0-1.0/Metric Ton

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

       Inquiry Now

  • 10,13-dimethyl-6-methylene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione

  • Casno:

    107868-30-4

    10,13-dimethyl-6-methylene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione

    Min.Order: 10 Milligram

    FOB Price:  USD $ 0.0-0.0/Milligram

    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

  •  Amadis Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

       Inquiry Now

  • Exemestone

  • Casno:

    107868-30-4

    Exemestone

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0/Metric Ton

    High quality, low price. We can provide free sample for test. After shipment, keep sample for 3 years. Packing as your request, with photo before shipment. Fast delivery, tracking number available, first-class service to customers. Facto

    Hubei Danjiangkou Danao pharmaceutical Chemical Co.,Ltd is located in famous Taoist Holy Place-Wudang Mountain. It is next to the middle origin of South-to-North Water Diversion Pr

  •  Hubei Danao Pharmaceutical Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-719-5251167

    Address:Fandan Road,Danjiangkou,Hubei

       Inquiry Now

  • tianfu-chem_	Exemestane 107868-30-4

  • Casno:

    107868-30-4

    tianfu-chem_ Exemestane 107868-30-4

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

       Inquiry Now

  • Pharmaceutical Grade CAS 107868-30-4 with best quality

  • Casno:

    107868-30-4

    Pharmaceutical Grade CAS 107868-30-4 with best quality

    Min.Order: 10 Gram

    FOB Price:  USD $ 146.0-176.0/Gram

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • BLOOM TECH Advanced API/Technology support Exemestane CAS 107868-30-4

  • Casno:

    107868-30-4

    MSDS/COA Download

    BLOOM TECH Advanced API/Technology support Exemestane CAS 107868-30-4

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Inquiry guide 1.Please send the quantity(Weight) to us, we will arrange our sales to provide the one-for-one service for you. 2.Then we will provide the professional quotation list for you, it will be including all the factors in who

    WHO WE ARE 1.We Focus on the technology of Organic Synthesis since 2008. 2.API/Pharmaceutical intermediate/Fine chemical/New material/Extraction etc. 3.Chemical reagent: Over 300,0

  •  Shaanxi BLOOM TECH Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-29-86470566

    Address:Block A of Central Mansion, No.113 of Weiyang Rd, ETDZ, Xi'an, Shaanxi 710016, China

       Inquiry Now

  • Exemestane/ LIDE PHARMA- Factory supply / Best price

  • Casno:

    107868-30-4

    Exemestane/ LIDE PHARMA- Factory supply / Best price

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&

    LIDE PHARMACEUTICALS LIMITED is one of the fastest growing pharmaceutical company in China. We have developed strategic partnership with our manufacturing associates having state o

  •  LIDE PHARMACEUTICALS LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-25-58409506

    Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.

       Inquiry Now

  • Exemestane discount  wholesale

  • Casno:

    107868-30-4

    Exemestane discount wholesale

    Min.Order: 1 Gram

    FOB Price:  USD $ 15.0-15.0/Gram

    Antimex Group, was founded in 2001,we are specializing in manufacturing & researching, warehouse & logistics of Active pharmaceutical Ingredients, pharmaceutical and chemical raw materials, Veterinary pharm APIs, food and feed additives

    Antimex Chemical Limied, was founded in 2001, we are specializing in manufacturing & researching of Active pharmaceutical Ingredients,Veterinary pharm APIs,cosmetic ingredients,and

  •  Antimex Chemical Limied

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-50563169

    Address:Room1027,No.Jinyu Road,Pudong

       Inquiry Now

  • 6-Methyleneandrosta-1,4-diene-3,17-dione

  • Casno:

    107868-30-4

    MSDS/COA Download

    6-Methyleneandrosta-1,4-diene-3,17-dione

    Min.Order: 10 Gram

    FOB Price:  USD $ 4.0-10.0/Gram

    We are HUBEI AOKS TRADE CO.; LTD. I am sales1 IF YOU ARE INTERESTED IN OUR PRODUCTS, PLEASE FEEL FREE TO CONTACT US. Our Superiority: 1 Best service, high quality and reasonable price 2.It's customers'

    HUBEI AOKS TRADE CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and dy

  •  HUBEI AOKS BIO-TECH CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-27-52345788

    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

       Inquiry Now

  • High purity Exemestane CAS No.:107868-30-4

  • Casno:

    107868-30-4

    High purity Exemestane CAS No.:107868-30-4

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 2.0-2.0/Kilogram

    Exemestane CAS No.:107868-30-4 Name: Exemestane Synonyms: 6-Methylenandrosta-1,4-diene-3,17-dione; 10,13-Dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene- Molecular Structure Mole

    HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketi

  •  Hangzhou Think Chemical Co. Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-571-89986307/81956191/81956084/81956192

    Address:Room 719 Building D Meidu Plaza 789 Moganshan Road

       Inquiry Now

  • 6-Methyleneandrosta-1,4-diene-3,17-dione 107868-30-4

  • Casno:

    107868-30-4

    6-Methyleneandrosta-1,4-diene-3,17-dione 107868-30-4

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

       Inquiry Now

  • Exemestane

  • Casno:

    107868-30-4

    Exemestane

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers

    Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wu Han City where is a traffic hinge of China, is a big integrative chemical enterprise being engaged in producing and

  •  Wuhan Fortuna Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-27-59207850

    Address:A2705,Dong Yi Shi Qu,129# XinHua Road,WuHan,China

       Inquiry Now

  • An antineoplastic drugs Exemestane CAS:107868-30-4

  • Casno:

    107868-30-4

    An antineoplastic drugs Exemestane CAS:107868-30-4

    Min.Order: 20 Gram

    FOB Price:  USD $ 81.0-94.0/Gram

    Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

    Baoji Guokang Healthchem co.,ltd located in Baoji High-tech Zone,is epitomizing international,cooperative and honest.We are a young company full of action and energy,and our profes

  •  Baoji Guokang Healthchem co.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-917-3909592

    Address:China

       Inquiry Now

  • Nice Quality Exemestane CAS RN	107868-30-4

  • Casno:

    107868-30-4

    MSDS/COA Download

    Nice Quality Exemestane CAS RN 107868-30-4

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-3.0/Gram

    Our Service: 1. Best quality in your requirement 2. Competitive price in china market 3. Mature technical support 4. Professional logistic support 5 . Full experience of large numberscontainers loading in chinese sea port 6 .Fast

    Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kind

  •  Wuhan Monad Medicine Tech Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8613397160123

    Address:13th Floor, Tower B, Century Plaza, Zhongnan Road, Wuchang District, Wuhan, China.

       Inquiry Now

  • Exemestane/ Aromasin

  • Casno:

    107868-30-4

    Exemestane/ Aromasin

    Min.Order: 20 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1.High Quality: Quality is life. Quality is the most important element for all goods. We have a lab doing research in Wuhan China and produce sarms in bulk quantity. We have 8 years experience making all kinds of sarms. And all our old customers

    WUHAN WONDA PHARMACEUTICAL AND CHEMICAL LIMITED is specializing in custom synthesis, manufacture and import & export of nootropics, herbal extract, OLED etc. Wuhan Wonda Pharm & Ch

  •  Wuhan Wonda Pharm Limited

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:027-84306245

    Address:Wuhan Private Science and Technology Park , Wuhan, China

       Inquiry Now

  • Exemestane powder

  • Casno:

    107868-30-4

    Exemestane powder

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 20.0-20.0/Kilogram

    Before-Sale Service: ---Any inquiries will be replied within 50 hours. ---Golden Manufactory under ISO/GMP with large stock. ---Dedication to quality,We have strict quality control system. ---OEM/ODM Available. ---Sample is available for yo

    Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is

  •  Xi'an Harmonious Natural Bio-Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-029-86712509

    Address:huilinhuacheng 10-2104

       Inquiry Now

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Specification

The Exemestane, with the CAS registry number 107868-30-4, is also known as 6-Methylenandrosta-1,4-diene-3,17-dione; 10,13-Dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-. It belongs to the product categories of Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Pfizer compounds;Steroid and Hormone.This chemical's molecular formula is C20H24O2 and molecular weight is 296.40. What's more,Its systematic name is 6-Methyleneandrosta-1,4-diene-3,17-dione.It is a white to light yellow crystal powder.Exemestane is used as an antineoplastic.An oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive breast cancer in postmenopausal women.

Physical properties about Exemestane are:
(1)ACD/LogP: 2.432; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.43; (4)ACD/LogD (pH 7.4): 2.43; (5)ACD/BCF (pH 5.5): 41.52; (6)ACD/BCF (pH 7.4): 41.52; (7)ACD/KOC (pH 5.5): 501.13; (8)ACD/KOC (pH 7.4): 501.13; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Index of Refraction: 1.572; (13)Molar Refractivity: 85.797 cm3; (14)Molar Volume: 260.59 cm3; (15)Surface Tension: 42.9010009765625 dyne/cm; (16)Density: 1.137 g/cm3; (17)Flash Point: 168.985 °C; (18)Enthalpy of Vaporization: 71.317 kJ/mol; (19)Boiling Point: 453.719 °C at 760 mmHg; (20)Vapour Pressure: 0 mmHg at 25°C.

Preparation of Exemestane:
Triethyl orthoformate and ethanol are dissolved in tetrahydrofuran.In the presence of p-toluenesulfonic acid reaction,add N-methyl aniline and formaldehyde solution to continue to respond. The Mannich reaction products are soluble in benzoic acid and anhydrous 2 chew alkyl.Under the action of the DDQ,exemestane can be received, with a total yield of 45%. 

    Premium Related Products