3-Methyl-2H-1-benzopyran Potassium Channel Activators

DOI: 10.1021/jm00114a017

Source and publish data:

Journal of Medicinal Chemistry p. 3074 - 3085 (1991)

Update date:2022-08-03

Topics:

Authors:

Gericke, Rolf

Harting, Juergen

Lues, Inge

Schittenhelm, Christine

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Article abstract of DOI:10.1021/jm00114a017

By aldol condensation of 4-chromanones with paraformaldehyde, 3-alkylenechromanones 10 were obtained which gave 3-alkylchromenes following reduction and dehydration.Subsequent 3-chloroperbenzoic acid oxidation produced the versatile epoxide intermediates

Full text of DOI:10.1021/jm00114a017

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