Synthesis of 8-aryl-substituted coumarins based on ring-closing metathesis and Suzuki-Miyaura coupling: Synthesis of a furyl coumarin natural product from Galipea panamensis

DOI: 10.1021/jo2026564

Source and publish data:

Journal of Organic Chemistry p. 2360 - 2367 (2012)

Update date:2022-07-29

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Authors:

Schmidt, Bernd

Krehl, Stefan

Kelling, Alexandra

Schilde, Uwe

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Article abstract of DOI:10.1021/jo2026564

The synthesis of 7-methoxy-8-(4-methyl-3-furyl)-2H-chromen-2-one, a natural product with antileishmanial activity recently isolated from the plant Galipea panamensis, is described. The key step is a Suzuki-Miyaura coupling of a furan-3-boronic acid and an

Full text of DOI:10.1021/jo2026564

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