A Synthesis of Natural α-Tocopherol Intermediate

DOI: 10.1016/S0957-4166(00)82122-9

Source and publish data:

Tetrahedron Asymmetry p. 371 - 376 (1991)

Update date:2022-08-03

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Authors:

Sugai, Takeshi

Watanabe, Naoyuki

Ohta, Hiromichi

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Article abstract of DOI:10.1016/S0957-4166(00)82122-9

(S)-(-)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanmethanol, an intermediate of natural α-tocopherol was synthesized from (S)-2-benzyloxy-2-methyl-4-pentenoic acid, which was obtained by the enzymatic hydrolysis of the corresponding racemic methyl ester.

Full text of DOI:10.1016/S0957-4166(00)82122-9

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