Regioselective Synthesis of Δ6-, Δ7-, and Δ8-14α-Cyanosterol Derivatives: Versatile Precursors to 14α-Demethylase Inhibitors

DOI: 10.1021/jo00038a024

Source and publish data:

Journal of Organic Chemistry p. 3347 - 3353 (1992)

Update date:2022-09-26

Topics:

Authors:

Gallagher, Timothy F.

Adams, Jerry L.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00038a024

The efficient preparation of 3β-(benzoyloxy)-4,4-dimethyl-5α-cholest-8(14)-en-7-one (4a) and 3β-(benzyloxy)-5α-ergosta-8(14),22-dien-7-one (4b) and their conversion to Δ⁶-, Δ⁷- or Δ⁸-14α-functionalized sterols is reported.

Full text of DOI:10.1021/jo00038a024

Products guided by the article

Product name:Benzoic acid (3S,5R,8R,9R,10S,13R,14S,17R)-10,13-dimethyl-7-oxo-17-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-tetradecahydro-20-oxa-cyclopropa[8,14]cyclopenta[a]phenanthren-3-yl ester

Cas No:136209-57-9

R&D Labs maybe for 136209-57-9

Guangzhou Probig Fine Chemical Co., Ltd.

Contact:020-86297874

Address:No.2, 1/F, No.20, Hetai Road,Hebian Village, Baiyun District,Guangzhou,China
Suzhou Credit International Trading Co., Ltd

Contact:+86-512-65398039

Address:Qingdeng, Hightech. District, Suzhou
Suns Chemical Sdn Bhd

Contact:0086 371 65711996

Address:Jalan 4/3, Kawasan Perindustrian Serendah, 48000 Rawang,
Jiaxing Anrui Material Technology Co., Ltd.

Contact:86-573-82651652 13305832579

Address:Room 407, Technology Building, 1369 Chennan Road, Jiaxing City, Zhejiang, China
Shanggao Ruiya Fine Chemicals Co., Ltd

Contact:+86-795-2592103

Address:Xingguang Nanlu,Shanggao County Industry Park

Relevant to this article

2,4-Dinitro-trans-cinnamic acid

Doi:10.1107/S0108270196012310
(1997)
(E)-4,8-DIMETHYL-1,3,7-NONATRIENE AND (E,E)-4,8,12-TRIMETHYL-1,3,7,11-TRIDECATETRAENE, TWO UNUSUAL HYDROCARBONS FROM CARDAMOM OIL

Doi:10.1016/S0040-4039(00)84461-5
(1986)
Doi:10.1021/jo01116a615
(1956)
Doi:10.1021/jo01065a012
(1961)
Rhodium(III)-catalyzed intermolecular direct amidation of aldehyde C-H bonds with N -chloroamines at room temperature

Doi:10.1021/ol400921r
(2013)
Doi:10.1021/jo01280a005
(1967)

Article Doi