Catalytic asymmetric addition of organolithiums to aldimines

Article abstract of DOI:10.1016/0040-4039(91)80698-6

An asymmetric 1,2-addition of organolithiums to imines (1) was catalyzed by a substoichiometric amount (0.05~0.3 equivalent) of a chiral aminoether (2) to provide the corresponding optically active amines (3).