Carbonyl Addition and Alkylation Reactions of Isothiazolidine 1-Oxide, the Sulfur Analog of 2-Pyrrolidone

Article abstract of DOI:10.1021/jo00055a024

Isothiazolidine 1-oxide is the sulfur analog of 2-pyrrolidone.A series of reactions at both the nitrogen and the α-sulfinyl carbon have been carried out.N-Deprotonation under phase-transfer conditions in the presence of p-nitrobenzyl bromide gives 2-(p-ni