Dipeptide Side-Chain Chain Hydrophobic Interactions as Conformational Core for Chymotrypsin Inhibition

Article abstract of DOI:10.1246/bcsj.64.2519

A series of dipeptides with the sequence H-D-Leu-L-Phe-R denotes 4-phenylpiperidide, 4-phenylpiperazide, and their derivatives, have been synthesized to examine their ability to inhibit chymotrypsin.Dipeptide phenylpiperidide and phenylpiperazide inhibite