Tetrahedron Letters p. 4249 - 4250 (1991)
Update date:2022-07-31
Topics:
Chenevert, Robert
Desjardins, Michel
Both enantiomers of baclofen have been synthesized in five steps from 4-chlorocinnamic acid. The key step is the highly stereoselective enzymatic hydrolysis of dimethyl 3-(4-chlorophenyl)glutarate by chymotrypsin.
View MoreContact:0086-29-89196322
Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
Jinzhou Jiutai Pharmaceutical Co.,Ltd
Contact:+86-0416-5179890
Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd
Contact:+86-311-80817929
Address:Shangzhuang,Shijiazhuang,China
Chengdu CSH Pharmaceutical Co.,ltd
Contact:+86-(28)-85321971
Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
Shanghai Yuking Water Soluble Material Tech Co., Ltd
Contact:86-21-68286299
Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China
Doi:10.1021/om200362v
(2011)Doi:10.1080/00397910902981274
(2010)Doi:10.1016/S0040-4039(00)80788-1
(1988)Doi:10.1002/mrc.1260291018
(1991)Doi:10.1021/ja910090v
(2010)Doi:10.1134/S1070428011040178
(2011)
