The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistry

DOI: 10.1016/j.bmcl.2012.03.052

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3152 - 3156 (2012)

Update date:2022-07-30

Topics:

Authors:

Huang, Baohua

Kukowska-Latallo, Jolanta F.

Tang, Shengzhuang

Zong, Hong

Johnson, Kali B.

Desai, Ankur

Gordon, Chris L.

Leroueil, Pascale R.

Baker Jr., James R.

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Article abstract of DOI:10.1016/j.bmcl.2012.03.052

The facile conjugation of three azido modified functionalities, namely a therapeutic drug (methotrexate), a targeting moiety (folic acid), and an imaging agent (fluorescein) with a G5 PAMAM dendrimer scaffold with cyclooctyne molecules at the surface thro

Full text of DOI:10.1016/j.bmcl.2012.03.052

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