13902-54-0Relevant articles and documents
SESQUITERPENE LACTONES OF Artemisia pauciflora
Adekenov, S. M.,Kagarlitskii, A. D.,Mukhametzhanov, M. N.,Kupriyanov, A. N.
, p. 234 - 235 (1983)
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Synthesis of 6-epi-tuberiferin and the biological activities of tuberiferin, dehydrobrabrachylaenolide, 6-epi-tuberiferin, and their synthetic intermediates
Li, Dan,Higuchi, Yohsuke,Kobayashi, Takafumi,Shimoma, Fumito,Bai, Yuhua,Ando, Masayoshi
, (2021/02/02)
Tuberiferin, 6-epi-tuberifelin, dehydrobrachylaenolide and two series of eudesmanolides, eudesmane-12,6 α-lactones and eudesmane-12,6β-lactones, were synthesized for the studies of the structure–activity relationships to explore novel anti-inflammatory, a
Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening
Franke, Lutz,Schwarz, Oliver,Müller-Kuhrt, Lutz,Hoernig, Christina,Fischer, Lutz,George, Sven,Tanrikulu, Yusuf,Schneider, Petra,Werz, Oliver,Steinhilber, Dieter,Schneider, Gisbert
, p. 2640 - 2646 (2008/02/06)
A natural product collection and natural-product-derived combinatorial libraries were virtually screened for potential inhibitors of human 5-lipoxygenase (5-LO) activity. We followed a sequential ligand-based approach in two steps. First, similarity searc
Synthesis of (+)-8-Deoxyvernolepin
Hernandez, Rosendo,Valazquez, Silvia M.,Suarez, Ernesto,Rodriguez, Maria S.
, p. 6395 - 6403 (2007/10/02)
A short and efficient synthesis of (+)-8-deoxyvernolepin (2) from (-)-α-santonin (8), by functionalization of the angular methyl from a 2β- or 6β-alkoxy radical generated by reaction of the alcohol 6 or 7 with diphenylhydroxyselenium acetate and iodine and 1,4-fragmentation of the γ-hydroxystannane 35 using hypervalent organoiodine reagents as the key steps, is described.The most important structural features of this compound and other vernolepin congeners, the δ-valerolactone cis-fused to ring B moiety and the angular vinyl group, are introduced in the same step.
