
Journal of the Chemical Society. Perkin transactions I p. 2565 - 2574 (1991)
Update date:2022-07-29
Topics:
Kennedy, Michael
McKervey, M. Anthony
Rhodium(II) mandelate-catalysed cyclisation of α-diazoketones derived from 3-arylpropionic acids produces bicyclo<5.3.0>decatrienones, one of which has been used to synthesise an advanced (+/-)-confertin intermediate in six stages and 20percent overall yield.The possibility of constructing intermediates for the synthesis of damsin-like pseudoguaianolides via catalysed diazoketone cyclisation is also examined and methods for the construction of polyfunctional 3-arylpropionic acids suitable for use as damsin precursors are presented.
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