Tetrahedron Letters p. 5263 - 5264 (1991)
Update date:2022-08-04
Topics:
Rivero
Greenlee
Patchett
As part of an effort to design human renin inhibitors with improved bioavailability, the amino-terminal Phe-His element present in many classes of renin inhibitors was replaced by a sulfone containing isostere.
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Doi:10.1016/S0040-4039(00)79437-8
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(2017)Doi:10.1002/adsc.201301144
(2014)Doi:10.1016/j.carres.2012.02.021
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