Journal of Medicinal Chemistry p. 1130 - 1136 (1992)
Update date:2022-09-26
Topics: Synthesis Reaction Potent Chemical Reaction Activity Chemical compound Antiinflammatory
Kuroda
Suzuki
Tamura
Ohmori
Hosoe
New antiinflammatory agents 4-hydroxy-2(1H)-oxo-1-phenyl-1,8- naphthyridine-3-carboxamides 7 were designed and synthesized via a valuable intermediate, 1-phenyl-2H-pyrido[2,3-d][1,3]oxazine-2,4(1H)-dione (9). The nature of substituents on the amide nitrog
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