ENANTIOSELECTIVE SYNTHESIS OF FOUR ISOMERIC BUILDING BLOCKS USEFUL IN THE SYNTHESIS OF 2-NOR-LEUKOTRIENE ANALOGUES

Article abstract of DOI:10.1016/S0957-4166(00)80273-6

We report, in this letter, the enantioselective synthesis of four isomeric functionalized epoxides (3a, 3b, 3c and 3d) which are useful building blocks for the synthesis of 2-nor-leukotriene analogues.All four epoxides are formally derived from a single n