LDA-catalyzed diastereoselective Michael-additions with glycine derivatives: Synthesis of 4-substituted 3-aryl-N(diphenylmethylene)glutamates followed by cyclization to 4-substituted 3-aryl-2-ethoxycarbonyl-5-oxo-pyrrolidines

DOI: 10.1002/ardp.2503241210

Source and publish data:

Archiv der Pharmazie p. 989 - 995 (1991)

Update date:2022-08-04

Topics:

Authors:

Pachaly Pachaly

Kang Kang

Wahl Wahl

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/ardp.2503241210

Synthesis and stereochemistry of 4-substituted diethyl 3-aryl-N(diphenylmethylene)glutamate 3 by LDA-catalyzed Michael addition of ethyl-N(diphenylmethylene)glycinate with diethylbenzylidene-malonate or ethyl-2-cyanocinnamates, respectively. are reported.

Full text of DOI:10.1002/ardp.2503241210

Products guided by the article

Product name:4-Cyan-2-N-(Diphenylmethylen)-3-phenylglutaminsaeurediethylester

Cas No:138875-75-9

R&D Labs maybe for 138875-75-9

Hangzhou TJM Chemical Trade Co., Ltd

Contact:86-571-88223276 86-13388481653

Address:2221#,Boyuexuan,1860# Binsheng Road,Binjiang District, Hangzhou CityZhejiang Province, 310051, P. R. China
Meryer (Shanghai) Chemical Technology Co., Ltd.

website:http://www.meryer.com/cn/index/

Contact:+86-755-86170518

Address:Minhang,Shanghai, China
Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
RongCheng Tianyu Technology Co.,Ltd.

Contact:86-631-7519595

Address:220Ping Donghai Road RongChengCity,ShangDong Province China
Nanjing Yuance Industry&Trade Co., Ltd.

website:http://www.njyuance.cn/

Contact:+86-25-85439097

Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China

Relevant to this article

Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)- furanones

Doi:10.1021/jm00085a003
(1992)
Template-directed interference footprinting of protein-phosphate contacts in DNA

Doi:10.1021/ol006792j
(2001)
Novel oxidation of proline derivatives to pyrroles by hypervalent iodine

Doi:10.1080/00397919808004414
(1998)
Studies of Azetidin-2-one as a Reactive Enolate Synthon of β-Alanine for Condensations with Aldehydes and Ketones

Doi:10.1021/acs.joc.6b01585
(2016)
Synthesis of 3-adenyl- and 3-thyminylcyclobutane-1,1-dimethanols and their homo-octameric phosphodiesters

Doi:10.1002/hlca.19920750216
(1992)
Facile synthesis of hybrid sulfonophosphinodipeptides composing of taurines and 1-aminoalkylphosphinic acids

Doi:10.1007/s00726-011-1098-5
(2012)

Article Doi