Bioorganic and Medicinal Chemistry Letters p. 2866 - 2869 (2016)
Update date:2022-09-26
Topics:
Ogawa, Anthony K.
Bunte, Ellen Vande
Mal, Rudrajit
Lan, Ping
Sun, Zhongxiang
Crespo, Alejandro
Wiltsie, Judyann
Clemas, Joseph
Gibson, Jack
Contino, Lisa
Lisnock, Jeanmarie
Zhou, Gaochao
Garcia-Calvo, Margarita
Jochnowitz, Nina
Ma, Xiuying
Pan, Yi
Brown, Patricia
Zamlynny, Beata
Bateman, Thomas
Leung, Dennis
Xu, Ling
Tong, Xinchun
Liu, Kun
Crook, Martin
Sinclair, Peter
Reported herein are a series of reverse indoles that represent novel non-steroidal mineralocorticoid receptor (MR) antagonists. The key structure-activity relationships (SAR) are presented below. This reverse indole series is exemplified by a compound tha
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