A Facile Ring Transformation of 5-Aminopyrimidin-4(3H)-one into 2-Alkoxy-1H-imidazoles in the Presence of Oxidative Metal Salts and Alkyl Alcohols

DOI: 10.1039/c39910001688

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1688 - 1689 (1991)

Update date:2022-08-04

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Authors:

Matsuura, Izumi

Ueda, Taisei

Murakami, Nobutoshi

Nagai, Shin-ichi

Sakakibara, Jinsaku

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Article abstract of DOI:10.1039/c39910001688

5-Amino-6-methyl-3-phenylpyrimidin-4(3H)-one 1 was transformed into 2-alkoxy-1H-imidazoles 2a-f by treatment with various oxidative metals salts such as CuCl2, CuBr2, Cu(NO3)2, CuSO4, Tl(NO3)3, FeCl3 and Pb(OAc)4 in alkyl alcohols.

Full text of DOI:10.1039/c39910001688

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