Short and efficient synthesis of enantiomerically pure 4-substituted (1E,3E)-1[(R)-p-tolylsulfinyl]-1,3-butadiens

Article abstract of DOI:10.1055/s-1991-26633

The title compounds were readily prepared in two steps by the condensation of (+)-methyl-p-tolyl (R)-sulfoxide to α,β-unsaturated aldehydes followed by a one-pot dehydration of the resulting β-hydroxy sulfoxides.