Degradation of 3-aryl-2-hydroxyiminopropionic acids into arylacetonitriles using 1,1'-carbonyldiimidazole or 2,2'-oxalyldi(o-sulfobenzimide)

DOI: 10.1248/cpb.39.3030

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3030 - 3033 (1991)

Update date:2022-07-30

Topics:

Authors:

Kitagawa

Kawaguchi

Inoue Inoue

Katayama

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Article abstract of DOI:10.1248/cpb.39.3030

1,1'-Carbonyldiimidazole (1) is a useful reagent for the preparation of arylacetonitriles (9) from 3-aryl-2-hydroxyiminopropionic acids (8), and 2,2'-oxalyldi (o-sulfobenzimide) (2) can also be used for this purpose under essentially neutral conditions.

Full text of DOI:10.1248/cpb.39.3030

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