
Tetrahedron p. 9901 - 9914 (1991)
Update date:2022-07-30
Topics:
Chadwick
Ennis
A general method for the synthesis of 2-(2-heteroaryl)imidazolines (1a-c) has been developed and subsequent metallation studies have shown the imidazole group to be a strong director of ortho-metallation. The synthetic utility of lithio intermediates (5) and (7) has been shown by reaction with a series of electrophiles.
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Doi:10.1016/0040-4039(91)80577-S
(1991)Doi:10.1016/j.phytochem.2012.05.024
(2012)Doi:10.1039/c2ob25518a
(2012)Doi:10.1002/ardp.201500317
(2016)Doi:10.1016/j.tet.2019.05.040
(2019)Doi:10.1016/j.bmc.2009.10.051
(2010)