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Organic & Biomolecular Chemistry
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3,4-Diethyl-1-methylisoquinoline (3ad)10f,13b: Yellow liquid; b. p.
140–142 °C; 1H NMR (400 MHz, CDCl3) δ 8.06 (d, J = 8.0 Hz, 1H),
7.96 (d, J = 8.3 Hz, 1H), 7.64 (t, J = 7.3 Hz, 1H), 7.48 (t, J = 7.4 Hz,
1H), 3.06 – 2.90 (m, 7H), 1.35 – 1.25 (m, 6H); 13C NMR (101 MHz,
CDCl3) δ 155.72, 152.47, 135.14, 129.48, 127.19, 126.11, 126.05,
125.25, 123.32, 28.40, 22.26, 20.64, 15.20, 14.88; GCMS (EI 70 eV)
m/z (% rel. inten.) 199 (M+), 198, 184, 170, 128, 91.
DOI: 10.1039/C9OB00174C
Adv. Synth. Catal., 2014, 356, 1461.
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1-Methyl-3,4-dip-tolylisoquinoline (3ae)11c,11j: White solid; m. p.
134-136 oC; 1H NMR (400 MHz, CDCl3) δ 8.17 – 8.15 (m, 1H), 7.66
– 7.63 (m, 1H), 7.56 – 7.53 (m, 2H), 7.27 – 7.24 (m, 2H), 7.16 – 7.09
(m, 4H), 7.00 – 6.98 (m, 2H), 3.06 (s, 3H), 2.38 (s, 3H), 2.27 (s, 3H);
13C NMR (101 MHz, CDCl3) δ 157.37, 149.16, 137.96, 136.61,
136.49, 136.29, 134.53, 131.16, 130.12, 129.79, 128.92, 128.31,
126.30, 126.26, 126.01, 125.46, 22.55, 21.26, 21.14; GCMS (EI 70
eV) m/z (% rel. inten.) 323 (M+), 322, 307, 265, 153, 146, 132.
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Conflicts of interest
There are no conflicts to declare.
Acknowledgements
The author D.S.D. would like to thank University Grant
Commission (UGC), New Delhi, India for providing a Senior
Research Fellowship under Basic Science Research (BSR)
scheme [F.25-1/2014-15(BSR)/F.7-227/2009 (BSR), 16th Feb
2015].
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