Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation

DOI: 10.1021/jm00085a013

Source and publish data:

Journal of Medicinal Chemistry p. 1259 - 1266 (1992)

Update date:2022-08-04

Topics:

Authors:

Fournie-Zaluski

Coric Coric

Turcaud Turcaud

Bruetschy

Lucas Lucas

Noble Noble

Roques Roques

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00085a013

Derivatives of amino acids bearing various zinc-coordinating moieties (SH, COOH, CONHOH, and PO₃H₂) were synthesized and tested for their ability to inhibit aminopeptidase N (APN). Among them, β-amino thiols were found to be the most

Full text of DOI:10.1021/jm00085a013

Products guided by the article

Product name:Benzenebutanamide, b-amino-N-hydroxy-, (S)-

Cas No:139428-66-3

R&D Labs maybe for 139428-66-3

Jiaxing Anrui Material Technology Co., Ltd.

Contact:86-573-82651652 13305832579

Address:Room 407, Technology Building, 1369 Chennan Road, Jiaxing City, Zhejiang, China
Daqing New Century Fine Chemical Co., Ltd.(expird)

Contact:010-57126694

Address:No.39, jinxing cun, honggang district
Shanghai Mintchem Development ., Ltd

Contact:0086 21 5190 8570

Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Shanghai agrotree chemical co.,ltd.

Contact:+86-21-50117563

Address:Room 8A,liangfeng building,No.8 dongfang RD.pudong,shanghai,China
Penglai Qianwei Chemical Co., Ltd.

Contact:86-535-3357802

Address:Shahelu (north), Penglai, Shandong, China

Relevant to this article

A convenient procedure for the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides and alkenes

Doi:10.1021/ol0514653
(2005)
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE₂ in LPS-induced RAW 264.7 cells

Doi:10.1016/j.bmcl.2017.03.057
(2017)
Studies in alkylation of 3-methyl-3-sulfolene and thermolysis of resulting 2-alkyl-3-sulfolenes: Convenient synthesis of 1,2-disubstituted-1,3-dienes

Doi:10.1016/S0040-4020(01)89010-4
(1992)
An improved procedure for the etherification of α-hydroxy acid derivatives

Doi:10.1080/00304940409458684
(2004)
ELECTROCHEMICAL REDUCTION OF TRANSITION METAL-SUBSTITUTED SILICON, GERMANIUM AND TIN DERIVATIVES I. COBALT OR COBALT AND IRON COMPLEXES

Doi:10.1016/0022-328X(84)80354-X
(1984)
Migratory insertion reactions of indenyliridium dialkyls and alkyl and aryl hydrides

Doi:10.1021/om00041a014
(1992)

Article Doi