Novel interleukin-5 inhibitors based on hydroxyethylaminomethyl-4H-chromen- 4-one scaffold

DOI: 10.1016/j.bmc.2012.08.006

Source and publish data:

Bioorganic and Medicinal Chemistry p. 5757 - 5762 (2012)

Update date:2022-09-26

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Authors:

Joo, Cheonik

Venkateswararao, Eeda

Lee, Ki-Cheul

Sharma, Vinay K.

Kyung, Min-Sik

Kim, Youngsoo

Jung, Sang-Hun

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Article abstract of DOI:10.1016/j.bmc.2012.08.006

Hydroxyethylaminomethyl-4H-chromenones were previously discovered as fairly strong IL-5 inhibitor. For determination of detail structure activity relationship, N-substituted hydroxyethylaminomethylchromenones 4a-n were prepared and evaluated for their IL-

Full text of DOI:10.1016/j.bmc.2012.08.006

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Product name:5-(cyclohexylmethoxy)-3-(((2-hydroxyethyl)(phenyl)amino)methyl)-4H-chromen-4-one

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