Synthesis of Dinucleoside Phosphates Containing Sulfur Substituted Nucleobases: 4-Thiouracil, 4-Thiothymine and 6-Mercaptopurine

DOI: 10.1016/S0040-4039(00)77675-1

Source and publish data:

Tetrahedron Letters p. 69 - 72 (1992)

Update date:2022-08-03

Topics:

Authors:

Clivio, Pascale

Fourrey, Jean-Louis

Gasche, Jeanette

Favre, Alain

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Article abstract of DOI:10.1016/S0040-4039(00)77675-1

S-Pivaloyloxymethylation of sulfur substituted nucleobases enables the synthesis in solution of dinucleoside phosphates containing sulfur modified residues such as 4-thiouracil, 4-thiothymine and 6-mercatopurine. Key words: 4-thiouracil; protection; phosphorylation; nucleosides.

Full text of DOI:10.1016/S0040-4039(00)77675-1

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