Synthesis of Quaternary Ammonium Fluoride Salts by a Solid-Liquid Halogen Exchange Process in Protic Solvents

Article abstract of DOI:10.1021/jo00281a024

Both hydrophilic and lipophilic quaternary ammomium fluoride compounds are prepared by direct exchange of the corresponding halides with solid potasium fluoride containing an optimized amount of water (4.0 mol percent).The procedure is most effective when methanol is applied as a solvent.A variety of quaternary ammonium fluorides were prepared in 75-97percent yield.