Tetrahedron Letters p. 1189 - 1192 (1992)
Update date:2022-08-02
Topics: Asymmetric synthesis Diastereoselectivity Column chromatography Yield NMR spectroscopy Enantiomeric excess (ee) Recrystallization Catalytic hydrogenation HPLC (high-performance liquid chromatography) Protecting group Azidation Chiral Auxiliary Reaction Optimization Enolate Vancomycin
Evans, David A.
Evrard, Deborah A.
Rychnovsky, Scott D.
Frueh, Thomas
Whittingham, William G.
DeVries, Keith M.
The asymmetric synthesis of vancomycin-related α-azido arylglycines by direct azide transfer methodology is reported.Procedures for the conversion of the azides to N-protected arylglycines are provided.
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