Propargyl and Allyl Grignard and Zinc Reagents. Regioselective Alkylation and Its Application to the Synthesis of PGE3 and F3α Methyl Ester

Article abstract of DOI:10.1021/jo00283a004

Regioselective propargylation and allylation were achieved using acylsilanes as electrophiles, and this methodology was applied to the synthesis of PGE₃ and F_3α methyl ester.