Synthesis p. 127 - 131 (1992)
Update date:2022-08-04
Topics:
Swiss
Hinkley
Maryanoff
Liotta
Complementary facial selectivity can be achieved in conjugate additions to γ-hydroxyenones by using either Grignard reagents or cuprates. In the case of the former, preliminary complexation of the magnesium reagent with the resident alkoxide, followed by alkyl group transfer, results in the exclusive formation of the syn product. Conversely, cuprate conjugate additions proceed in an anti fashion, presumably because, in this mode of addition, coulombic repulsions are minimized.
View MoreCeresking Ecology & Technology co.,ltd
Contact:86 22 66218397
Address:Room 1613, Zheshang Mansion, No. 1988, Yingbin Avenue, Binhai New District, Tianjin,China.
Jiangsu Allyrise Pharmaceutical Co., Ltd.(expird)
Contact:+86-523-86818997
Address:Taizhou,Jiangsu Province,CHINA
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Suzhou Credit International Trading Co., Ltd
Contact:+86-512-65398039
Address:Qingdeng, Hightech. District, Suzhou
chengdu firsterchem Pharmaceutical Co., Ltd.
Contact:028-66825849
Address:chengdu
Doi:10.1016/j.jfluchem.2012.07.010
(2012)Doi:10.1002/cjoc.201400528
(2014)Doi:10.1016/j.bioorg.2019.01.031
(2019)Doi:10.1021/jm301191p
(2012)Doi:10.1021/jo3021709
(2012)Doi:10.1002/hlca.19660490527
(1966)
