Pyridine-directed asymmetric hydrogenation of 1 1-diarylalkenes

DOI: 10.1021/acs.orglett.7b02262

Source and publish data:

Organic Letters p. 5062 - 5065 (2017)

Update date:2022-07-30

Topics:

Authors:

Yang, Hailong

Wang, Erfei

Yang, Ping

Lv, Hui Lv, Hui

Zhang, Xumu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/acs.orglett.7b02262

Highly enantioselective pyridine-directed rhodium-catalyzed asymmetric hydrogenation of challenging 1 1-diarylalkenes is achieved by using [Rh(NBD)DuanPhos]BF4 as a precatalyst. Various types of 2-pyridine substituted 1 1-diarylalkenes could be hydrogenated with good to excellent enantioselectivities which provide an efficient route to the synthesis of pharmaceutically and biologically active compounds containing a 2-pyridyl ethane unit.

Full text of DOI:10.1021/acs.orglett.7b02262

Products guided by the article

Product name:3-(1-(4-chlorophenyl)vinyl)pyridine

Cas No:1415681-25-2

R&D Labs maybe for 1415681-25-2

Feis International Trade Co,. Ltd

Contact:13961823444-18235944442

Address:Wuxi jiangsu
CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

website:http://www.czyys.com

Contact:0086-519-88802789

Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China
Ningbo J&S Botanics Inc.

Contact:86-574-26865651

Address:529 YuanBaoShan Road, Beilun District
Taizhou Chemedir Biopharm-tech Co., Ltd

Contact:+86 523 86200218

Address:G09, No. 1 Avenue China Medical City, Taizhou,Jiangsu, China
ANGCHEN BRIGHTCHEM CO., LTD

website:http://www.angchenchem.com

Contact:+86-510-88302099 82327577

Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China

Relevant to this article

Regioselective multicomponent sequential synthesis of hydantoins

Doi:10.1039/c2ob26498f
(2012)
Different inertness of titanocene [Cp₂Ti] and decamethyltitanocene [Cp*₂Ti] in reactions with N,N-bis(trimethylsilyl)sulfurdiimide - Elimination of tetramethylfulvene and formation of half-titanocene complexes

Doi:10.1002/ejic.201200242
(2012)
Symmetric anionic polymethine dyes derived from fluorene and its derivatives with electron-acceptor substituents: Synthesis and spectral properties

Doi:10.1007/s11172-012-0040-7
()
Synthesis of fluorinated cyclopropyl amino acid analogues: Toward the synthesis of original fluorinated peptidomimetics.

Doi:10.1021/jo302222n
(2013)
A cascade reaction actuated by nucleophilic heterocyclic carbene catalyzed intramolecular addition of enals via homoenolate to α,β-unsaturated esters: Efficient synthesis of coumarin derivatives

Doi:10.1021/ol303091m
(2013)
Integrated and segregated Au/γ-Fe₂O₃ binary nanoparticle assemblies

Doi:10.1002/anie.201207469
()

Article Doi