A cascade reaction actuated by nucleophilic heterocyclic carbene catalyzed intramolecular addition of enals via homoenolate to α,β-unsaturated esters: Efficient synthesis of coumarin derivatives

Article abstract of DOI:10.1021/ol303091m

A nucleophilic heterocyclic carbene mediated intramolecular homoenolate reaction strategy for the efficient synthesis of 4-alkyl substituted coumarins is described.