Rationally designed 'dipeptoid' analogues of CCK. Acid mimics of the potent and selective non-peptide CCK-B receptor antagonist CI-988

DOI: 10.1021/jm00092a007

Source and publish data:

Journal of Medicinal Chemistry p. 2573 - 2581 (1992)

Update date:2022-07-30

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Authors:

Drysdale

Pritchard

Horwell Horwell

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Article abstract of DOI:10.1021/jm00092a007

This paper outlines the synthesis of selected acid mimics of the non- peptide CCK-B selective antagonist CI-988, 1 CCK-B and CCK-A binding affinities of these analogues are described and their CCK-B affinity and selectivity rationalized by consideration o

Full text of DOI:10.1021/jm00092a007

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