Rationally designed 'dipeptoid' analogues of CCK. Acid mimics of the potent and selective non-peptide CCK-B receptor antagonist CI-988

Article abstract of DOI:10.1021/jm00092a007

This paper outlines the synthesis of selected acid mimics of the non- peptide CCK-B selective antagonist CI-988, 1 CCK-B and CCK-A binding affinities of these analogues are described and their CCK-B affinity and selectivity rationalized by consideration o