Stereospecific Total Syntheses of Decahydroquinoline Alkaloids (+/-)-195A and (+/-)-2-epi-195A

DOI: 10.1021/jo00041a012

Source and publish data:

Journal of Organic Chemistry p. 4103 - 4110 (1992)

Update date:2022-08-02

Topics:

Authors:

Polniaszek, Richard P.

Dillard, Lawrence W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00041a012

The total syntheses of decahydroquinoline alkaloids (+/-)-195A (pumiliotoxin C) and (+/-)-2-epi-195A are described.An unexpected, stereospecific epimerization of the C2 stereocenter of intermediate 6a occurred during its reduction.The isomerization result

Full text of DOI:10.1021/jo00041a012

Products guided by the article

Product name:(2S^*,4aR^*,5S^*,8aR^*)-1-benzyl-2-(1-propyl)-(Δ-3,4)-5-(dimethylphenylsilyl)-7-oxooctahydroquinoline

Cas No:142003-70-1

R&D Labs maybe for 142003-70-1

Nanjing Chemipioneer Pharma&Tech Co.,Ltd

website:http://www.chemipioneer.com.cn

Contact:+86-25-52685700

Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China
HANGZHOU YUNUO CHEMICAL CO.,LTD

website:http://www.yunuochem.com

Contact:0571-83715115

Address:hangzhou
Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Win-Win chemical Co.Ltd

website:http://www.win-winchemical.com

Contact:0086-577-64498589

Address:6F, No. 396 Xingping Road, Longwan Industrial Zone, Wenzhou City, Zhejiang, 325000 P.R.China
Xi'an Yuri Solar Co., Ltd

website:https://www.yurisolar.com/en

Contact:86--18092602675

Address:No. 560, East Hangtian Road, Xi'an, China

Relevant to this article

Dihydrooxazine oxides as key intermediates in organocatalytic michael additions of aldehydes to nitroalkenes

Doi:10.1002/anie.201204833
(2012)
Copper(II) cubane complexes built from electro- and photosensitive β-aminovinyl trifluoromethyl ketone ligands

Doi:10.1002/ejic.201200737
(2012)
Combination of phage display and molecular grafting generates highly specific tumor-targeting miniproteins

Doi:10.1002/anie.201203857
(2012)
Synthesis and characterization of trinuclear Ni^II₃ and Cu^II₃ triplesalophen complexes: Evaluation of ligand folding and heteroradialene formation and their impact on the magnetic properties

Doi:10.1002/ejic.201200990
(2012)
Gold(I)-catalyzed intramolecular [4 + 2] cycloaddition of ortho-(N-tethered 1,6-diynyl)benzaldehydes to 3,4-dihydrobenzo[f]isoquinolin-1(2H)-ones

Doi:10.1016/j.tetlet.2020.152200
(2020)
Trans-Dichlorobis{(1R,4S)-1,7,7-trimethyl-3-[(S)-α-methylbenzylimino] bicyclo[2.2.1]heptan-2-one-N}Palladium(II): Synthesis and structural examination

Doi:10.1134/S1070328413010107
(2013)

Article Doi