Stereospecific Total Syntheses of Decahydroquinoline Alkaloids (+/-)-195A and (+/-)-2-epi-195A

DOI: 10.1021/jo00041a012

Source and publish data:

Journal of Organic Chemistry p. 4103 - 4110 (1992)

Update date:2022-08-02

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Authors:

Polniaszek, Richard P.

Dillard, Lawrence W.

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Article abstract of DOI:10.1021/jo00041a012

The total syntheses of decahydroquinoline alkaloids (+/-)-195A (pumiliotoxin C) and (+/-)-2-epi-195A are described.An unexpected, stereospecific epimerization of the C2 stereocenter of intermediate 6a occurred during its reduction.The isomerization result

Full text of DOI:10.1021/jo00041a012

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