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61-90-5

Basic Information
CAS No.: 61-90-5
Name: L-Leucine
Molecular Structure:
Molecular Structure of 61-90-5 (L-Leucine)
Formula: C6H13NO2
Molecular Weight: 131.17
Synonyms: L(+)-Leucine;.alpha.-Aminoisocaproic acid;2-Amino-4-methylpentanoic acid, (S)-;L-Norvaline, 4-methyl-;L-alpha-Aminoisocaproic acid;Leucine (USP);2-Amino-4-methylvaleric acid (L);(2S)-alpha-Leucine;Pentanoic acid, 2-amino-4-methyl-, (S)-;(S)-2-Amino-4-methyl-pentanoic acid;Leucine, L-;2-Amino-4-methylpentanoic acid;(S)-(+)-leucine;Pentanoic acid, 2-amino-4-methyl-;Leu;Valeric acid, 2-amino-4-methyl-, (S)-;(2S)-2-azaniumyl-4-methyl-pentanoate;(S)-2-Amino-4-methylvaleric acid;(2S)-2-amino-4-methylpentanoic acid;Norvaline, 4-methyl-;L-Leuzin;L-2-Amino-4-methylpentanoic acid;(2S)-alpha-2-Amino-4-methylvaleric acid;FEMA No. 3297;2-Amino-4-methylpentanoic acid (L);(S)-leucine;
EINECS: 200-522-0
Density: 1.036 g/cm3
Melting Point: >300 °C(lit.)
Boiling Point: 225.8 °C at 760 mmHg
Flash Point: 90.3 °C
Solubility: 22.4 g/L (20 °C) in water
Appearance: White crystalline powder
Hazard Symbols:
Risk Codes:
Safety: 24/25
Transport Information:
PSA: 63.32000
LogP: 1.14470
Synthetic route
439912-47-7

Poc-Leu-OH

61-90-5

L-leucine

Conditions
ConditionsYield
With resin bound tetrathiomolybdate In methanol at 28℃; for 1.5h; ultrasonic bath;100%
13139-15-6

N-tert-butoxycarbonyl-L-leucine

61-90-5

L-leucine

Conditions
ConditionsYield
With water at 170℃; for 0.05h; Microwave irradiation;100%
With tetradecyl(trihexyl)phosphonium bistriflamide; trifluoroacetic acid at 130℃; for 0.166667h; Ionic liquid;98%
Multi-step reaction with 3 steps
1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate
2: trifluoroacetic acid
3: E. coli BL21 Star (DE3) S30 extract / aq. buffer / 6 h / 37 °C / pH 7.5
View Scheme
Multi-step reaction with 3 steps
1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate
2: trifluoroacetic acid
3: E. coli BL21 Star (DE3) S30 extract / aq. buffer / 6 h / 37 °C / pH 7.5
View Scheme
With trifluoroacetic acid In dichloromethane at 0 - 20℃; for 2h;

N-(L-leucyl)-β-D-glucopyranosylamine

61-90-5

L-leucine

Conditions
ConditionsYield
With pronase In water at 37℃; for 46h; Time; Enzymatic reaction;100%
2899-43-6

DL-leucine ethyl ester

61-90-5

L-leucine

Conditions
ConditionsYield
With 3,5-dinitrosalicylaldehyde; Alcalase In water; acetonitrile at 35℃; for 3h; pH=7.5; Enzymatic reaction; optical yield given as %ee;99%

(3S,5S)-3-Isobutyl-5-phenyl-morpholin-2-one

61-90-5

L-leucine

Conditions
ConditionsYield
With hydrogen; trifluoroacetic acid; palladium dihydroxide In methanol; water under 3750.3 Torr; for 24h;98%
111-26-2

hexan-1-amine

78641-71-1

(S)-2-(3,5-Dinitro-4-oxo-4H-pyridin-1-yl)-4-methyl-pentanoic acid

A

61-90-5

L-leucine

B

74197-48-1

1-hexyl-3,5-dinitro-4-pyridone

Conditions
ConditionsYield
In pyridine Product distribution;A 97%
B n/a
108437-94-1

(2S,5S)-N-<(S)-N-bis(methylthio)methyleneleucyl>-2,5-bis(methoxymethoxymethyl)pyrrolidine

61-90-5

L-leucine

Conditions
ConditionsYield
With hydrogenchloride for 4h; Heating;96%
328-39-2

LEUCINE

61-90-5

L-leucine

Conditions
ConditionsYield
In water at 37℃; for 2h; NADH, ammonium chloride, sodium formate, D-amino acid oxidase, catalase, leucine dehydrogenase, formate dehydrogenase, Tris-HCl buffer, pH 8.5;95%
With porcine kidney D-amino acid oxidase (EC 1.4.3.3.); sodium cyanoborohydride; flavin adenine dinucleotide In phosphate buffer at 37℃;90%
With D-amino acid oxidase; E. coli branched-chain amino acid aminotransferase In water at 37℃; for 72h; Tris buffer, pH 8.5, 1mM EDTA, monosodium glutamate, bovine serum albumin, catalase, pyridoxal 5'-phosphate;87%
98204-51-4

(S)-2-[{(allyloxy)carbonyl}amino]-4-methylpentanoic acid

61-90-5

L-leucine

Conditions
ConditionsYield
With tri-n-butyl-tin hydride; bis-triphenylphosphine-palladium(II) chloride In dichloromethane Ambient temperature;95%
26117-20-4

N-carbamoyl-L-leucine

61-90-5

L-leucine

Conditions
ConditionsYield
With NH4Cl-NH4OH buffer pH 8.5; nickel dichloride at 60℃; for 24h; N-carbamyl-L-amino acid aminohydrolase;94%
With Tris-HCl buffer; N-carbamoyl-L-amino acid hydrolase; iron(II) sulfate at 30℃; for 2h;
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 1h;
126306-95-4

Diphenyl-N-(benzyloxycarbonyl)-L-leucyl-(2-decarboxy-L-alanin-2-yl)phosphonat

A

61-90-5

L-leucine

B

60687-36-7

(R)-(1-aminoethyl)phosphonic acid

Conditions
ConditionsYield
With hydrogenchloride for 24h; Heating;A 10%
B 88%
72-18-4

L-valine

3190-70-3, 26334-33-8, 51018-87-2, 51248-35-2

L-Leucin-N-carbonsaeureanhydrid

A

61-90-5

L-leucine

B

686-50-0

L-leucyl-glycine

C

462-60-2

N-carbamoylglycine

D

oligomers of leu

oligomers of leu

Conditions
ConditionsYield
With water; potassium hydroxide; potassium borate buffer at 3℃; Product distribution; effect of use of various amino acid and NCA with various concentrations; effect of use various temp.; extent of hydrolysis;A n/a
B 87.1%
C n/a
D n/a
1258442-23-7

C72H135NO7

61-90-5

L-leucine

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane at 20℃;86%
161123-34-8

(SS,S)-2-(p-toluenesulfinylamino)-4-methylpentanenitrile

61-90-5

L-leucine

Conditions
ConditionsYield
With hydrogenchloride In water for 6h; Heating;85%
66866-66-8

phenylmethyl (4S)-4-(2-methylpropyl)-5-oxo-1,3-oxazolidine-3-carboxylate

61-90-5

L-leucine

Conditions
ConditionsYield
With boron trichloride In dichloromethane at 25℃; for 0.333333h;84%
10250-86-9

4-methyloxovaleric acid anion

61-90-5

L-leucine

Conditions
ConditionsYield
With ammonium formate; tris hydrochloride; nicotinamide adenine dinucleotide; formate dehydrogenase; phenylalanine dehydrogenase In water at 30℃; for 24h;83%
With L-glutamic acid; pyridoxal 5'-phosphate In water at 40℃; for 18h; E.coli Aspartate transaminase, pH 8;40%
631921-66-9

((S)-1-Cyano-3-methyl-butyl)-carbamic acid methyl ester

61-90-5

L-leucine

Conditions
ConditionsYield
With hydrogenchloride In water for 7h; Heating;81%
1738-77-8

L-leucine benzyl ester p-toluenesulfonate

61-90-5

L-leucine

Conditions
ConditionsYield
With sodium hydrogen telluride In N,N-dimethyl-formamide at 70℃; for 3.5h;80%
2018-66-8

Z-Leu-OH

61-90-5

L-leucine

Conditions
ConditionsYield
With boron trichloride In dichloromethane at 25℃; for 0.333333h;77%
With hydrogen; palladium on activated charcoal In ethanol at 20℃; for 1h;22 mg
With cell extract of Sphingomonas paucimobilis SC 16113 In water at 42℃; for 20h; Enzymatic reaction;100 % Chromat.
With ethylenediaminetetraacetic acid; phenylmethylsulphonyl fluoride; water In aq. phosphate buffer at 30℃; Kinetics; Reagent/catalyst; Microbiological reaction; Enzymatic reaction;
Multi-step reaction with 3 steps
1.1: triethylamine; isobutyl chloroformate / tetrahydrofuran / 0.5 h / Cooling with ice
1.2: 15 h / 10 - 35 °C
2.1: 2% active carbon-supported palladium; hydrogen / methanol / 1 h / 10 - 35 °C / 760.05 Torr
3.1: pronase / water / 46 h / 37 °C / Enzymatic reaction
View Scheme
1374963-75-3

D,L-leucine benzyl ester hydrochloride

61-90-5

L-leucine

Conditions
ConditionsYield
Stage #1: D,L-leucine benzyl ester hydrochloride With lithium carbonate In water; tert-butyl alcohol at 23℃; for 0.166667h; Resolution of racemate;
Stage #2: With 2-Hydroxymethylpyridine; Alcalase; water; zinc(II) acetate dihydrate In tert-butyl alcohol at 23℃; for 4h; Resolution of racemate; Enzymatic reaction; optical yield given as %ee;
77%

Diphenyl-N-(benzyloxycarbonyl)-L-leucyl-(2-decarboxy-D-alanin-2-yl)phosphonat

A

61-90-5

L-leucine

B

66068-76-6

(S)-1-aminoethylphosphonic acid

Conditions
ConditionsYield
With hydrogenchloride for 16h; Heating;A 28%
B 70%
4502-00-5

sodium 4-methyl-2-oxovalerate

61-90-5

L-leucine

Conditions
ConditionsYield
With zinc(II) perchlorate; (R)-15-amino-methyl-14-hydroxy-5,5-dimethyl-2,8-dithia<9>(2,5)pyridinophane In methanol for 24h; Ambient temperature;68%
With leucine dehydrogenase Yield given;
67337-73-9

5-isobutyl-imidazolidine-2,4-dione

61-90-5

L-leucine

Conditions
ConditionsYield
With sodium hydroxide; air at 30℃; for 72h; Pseudomonas sp. Strain NS671;68%
95853-80-8

(2S)-(+)-2-<(1S,2S)-(2-Hydroxy-1-hydroxymethyl-2-phenylethyl)amino>-4-methylvaleriansaeure

61-90-5

L-leucine

Conditions
ConditionsYield
With ammonium hydroxide; periodic acid In water for 14h; Ambient temperature;67%

C6H13NO2*H3N*ClH

61-90-5

L-leucine

Conditions
ConditionsYield
With ruthenium nanoparticles dispersed in a polyvinylpyrrolidone matrix; amberlyst A-21 In methanol; dichloromethane65%
18869-43-7

DL-leucine methyl ester

97985-98-3

p-methoxybenzyloxycarbonyl-Phe-OMe

A

61-90-5

L-leucine

B

150296-51-8

Moz-Phe-D-Leu-OMe

Conditions
ConditionsYield
Stage #1: DL-leucine methyl ester With Alcalase; water In tert-butyl alcohol at 25℃; pH=8.5; kinetic resolution;
Stage #2: p-methoxybenzyloxycarbonyl-Phe-OMe With Alcalase In tert-butyl alcohol Condensation;
A n/a
B 59%

1-(1-cyano-3-methyl-butylamino)-5-isopropenyl-2-methyl-cyclohexane-1,3-dicarbonitrile

61-90-5

L-leucine

Conditions
ConditionsYield
With hydrogenchloride at 110℃; for 12h;52%
64143-84-6

(2S)-(N-para-toluenesulphonylamino)-4-methylpentanoic acid tert-butyl ester

61-90-5

L-leucine

Conditions
ConditionsYield
With hydrogen bromide; acetic acid; phenol for 24h; Ambient temperature;49%
With hydrogen bromide; acetic acid 1.) phenol, 25 deg C, 24 h;
99-15-0

N-acetylleucine

61-90-5

L-leucine

Conditions
ConditionsYield
With sodium hydroxide; acylase Amano 30000 from Aspergillus spp. (30 u/mg); water; cobalt(II) chloride at 37 - 40℃; for 48h;39%
Herstellung mit Hilfe eines Enzym-Praeparats aus Aspergillus und Penicillium;
67-56-1

methanol

61-90-5

L-leucine

2666-93-5

(S)-Leu-OMe

Conditions
ConditionsYield
With thionyl chloride100%
With thionyl chloride100%
With thionyl chloride at 0 - 20℃;94%
64-17-5

ethanol

61-90-5

L-leucine

2743-60-4

L-Leucine ethyl ester

Conditions
ConditionsYield
With thionyl chloride100%
With amberlyst-15 Ambient temperature;77%
With thionyl chloride for 10h; Heating;70%
61-90-5

L-leucine

501-53-1

benzyl chloroformate

2018-66-8

Z-Leu-OH

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 20℃;100%
With sodium hydroxide at 0℃; for 1h;99%
With sodium hydroxide In water at 20℃; for 2h;92%
61-90-5

L-leucine

79-22-1

methyl chloroformate

74761-37-8

(S)-2-(methoxycarbonylamino)-4-methylpentanoic acid

Conditions
ConditionsYield
Stage #1: L-leucine; methyl chloroformate With sodium hydroxide In 1,4-dioxane; water at 0 - 60℃; for 18h; pH=8 - 9;
Stage #2: With hydrogenchloride In water
100%
Stage #1: L-leucine; methyl chloroformate With sodium hydroxide In water at 0 - 20℃;
Stage #2: With hydrogenchloride In water
84%
With alkali In water75%
61-90-5

L-leucine

99-33-2

3,5-dinitrobenoyl chloride

7495-01-4

(S)-N-(3,5-dinitrobenzoyl)leucine

Conditions
ConditionsYield
With methyloxirane In tetrahydrofuran at 25℃; for 0.25h;100%
With methyloxirane In tetrahydrofuran for 2h; Ambient temperature;94%
With sodium hydroxide
In tetrahydrofuran Ambient temperature; 7 - 10 days; Yield given;
50-00-0

formaldehyd

61-90-5

L-leucine

2439-37-4

(S)-2-dimethylamino-4-methyl-pentanoic acid

Conditions
ConditionsYield
With sodium cyanoborohydride; acetic acid In water; acetonitrile at 22℃; for 1h; pH=Ca.7; Inert atmosphere;100%
With sodium dihydrogenphosphate; zinc at 30℃; for 20h;95%
With sodium tetrahydroborate In 2,2,2-trifluoroethanol for 48h; Reflux;88%
61-90-5

L-leucine

24424-99-5

di-tert-butyl dicarbonate

13139-15-6

N-tert-butoxycarbonyl-L-leucine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 25℃; for 23h;100%
With sodium hydroxide In 1,4-dioxane; water at 0℃;100%
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 19h;99%
67-56-1

methanol

61-90-5

L-leucine

7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
Stage #1: methanol With thionyl chloride for 1h; Cooling with ice;
Stage #2: L-leucine at 20 - 66℃; for 6.5h;
100%
With thionyl chloride at 20℃; for 4h;99%
With thionyl chloride99%
61-90-5

L-leucine

22509-74-6

N-ethoxycarbonylphthalimide

2419-38-7

N-phthaloyl-(S)-leucine

Conditions
ConditionsYield
With sodium carbonate In water at 20℃; for 2h;100%
With sodium carbonate In water at 20℃; for 2h;100%
With sodium hydrogencarbonate In water for 1h; Ambient temperature;66%
With sodium carbonate In water35%
With sodium carbonate In water at 20℃; for 5h;
61-90-5

L-leucine

104-15-4

toluene-4-sulfonic acid

100-51-6

benzyl alcohol

1738-77-8

L-leucine benzyl ester p-toluenesulfonate

Conditions
ConditionsYield
In cyclohexane; water for 4h; Dean-Stark; Reflux;100%
In toluene for 20h; Reflux;85%
In toluene for 4h; Reflux; Inert atmosphere;82%
61-90-5

L-leucine

128-69-8

perylene-3,4,9,10-tetracarboxylic acid 3,4:9,10-dianhydride

N,N'-bis((S)-1-carboxy-3-methylbutyl)-3,4:9,10-perylenetetracarboxylic diimide

Conditions
ConditionsYield
With 1H-imidazole at 100℃; for 1h; Inert atmosphere;100%
With 1H-imidazole at 120℃; for 0.5h;97%
With 1H-imidazole at 120℃;95.4%
61-90-5

L-leucine

105-08-8

bis-1,4-(hydroxymethyl)cyclohexane

893447-84-2

L,L-leucine 1,4-cyclohexanedimethanol diester

Conditions
ConditionsYield
Stage #1: L-leucine; bis-1,4-(hydroxymethyl)cyclohexane With toluene-4-sulfonic acid In toluene at 150℃; for 30h; Heating / reflux;
Stage #2: With sodium hydrogencarbonate In water; toluene at 60℃;
100%
61-90-5

L-leucine

105-08-8

bis-1,4-(hydroxymethyl)cyclohexane

893447-84-2

L,L-leucine 1,4-cyclohexanedimethanol diester

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 20 - 150℃; for 30h; Heating / reflux;100%
878630-78-5

1-[(1-benzothien-2-ylcarbonyl)oxy]-2,5-pyrrolidinedione

61-90-5

L-leucine

215941-14-3

(benzo[b]thiophene-2-carbonyl)-l-leucine

Conditions
ConditionsYield
With triethylamine In ethanol; dichloromethane; water at 20℃;100%
Stage #1: 1-[(1-benzothien-2-ylcarbonyl)oxy]-2,5-pyrrolidinedione; L-leucine With triethylamine In ethanol; dichloromethane; water at 20℃;
Stage #2: With hydrogenchloride In dichloromethane; water
100%
Stage #1: 1-[(1-benzothien-2-ylcarbonyl)oxy]-2,5-pyrrolidinedione; L-leucine With triethylamine In ethanol; dichloromethane; water at 5 - 20℃; for 18.1667h;
Stage #2: With hydrogenchloride In ethanol; dichloromethane; water
With triethylamine In ethanol; dichloromethane; water at 5 - 20℃;
With triethylamine In ethanol; dichloromethane; water at 5 - 20℃;
61-90-5

L-leucine

63-91-2

L-phenylalanine

60-18-4

L-tyrosine

56-40-6

glycine

60117-24-0

H-Tyr-Gly-Gly-Phe-Leu-NH2

Conditions
ConditionsYield
Stage #1: L-tyrosine With BF4(1-)*C7H13N3Pol(1+); benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 25℃; for 1h; Ionic liquid; Automated synthesizer; solid phase reaction;
Stage #2: glycine In 1-methyl-pyrrolidin-2-one at 25℃; for 1h; Ionic liquid; Automated synthesizer; solid phase reaction;
Stage #3: L-leucine; L-phenylalanine Further stages;
100%
59985-82-9

5-phenylisoxazole-3-carbaldehyde

61-90-5

L-leucine

C16H17N2O3(1-)*Li(1+)

Conditions
ConditionsYield
With lithium hydride In methanol Reflux;100%
59985-82-9

5-phenylisoxazole-3-carbaldehyde

61-90-5

L-leucine

C16H17N2O3(1-)*Na(1+)

Conditions
ConditionsYield
With sodium methylate In methanol Reflux;100%
59985-82-9

5-phenylisoxazole-3-carbaldehyde

61-90-5

L-leucine

C16H17N2O3(1-)*Cs(1+)

Conditions
ConditionsYield
With caesium carbonate In methanol Reflux;100%
59985-82-9

5-phenylisoxazole-3-carbaldehyde

61-90-5

L-leucine

2C16H17N2O3(1-)*Ca(2+)

Conditions
ConditionsYield
With calcium hydride In methanol Reflux;100%
61-90-5

L-leucine

640292-02-0

5-(4-methylphenyl)-1,2-oxazole-3-carbaldehyde

C17H19N2O3(1-)*Li(1+)

Conditions
ConditionsYield
With lithium hydride In methanol Reflux;100%
61-90-5

L-leucine

640292-02-0

5-(4-methylphenyl)-1,2-oxazole-3-carbaldehyde

C17H19N2O3(1-)*Na(1+)

Conditions
ConditionsYield
With sodium methylate In methanol Reflux;100%
61-90-5

L-leucine

640292-02-0

5-(4-methylphenyl)-1,2-oxazole-3-carbaldehyde

C17H19N2O3(1-)*Cs(1+)

Conditions
ConditionsYield
With caesium carbonate In methanol Reflux;100%
61-90-5

L-leucine

640292-02-0

5-(4-methylphenyl)-1,2-oxazole-3-carbaldehyde

2C17H19N2O3(1-)*Ca(2+)

Conditions
ConditionsYield
With calcium hydride In methanol Reflux;100%
61-90-5

L-leucine

5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

1803-64-1

(3-oxobutanoyl)-L-leucine

Conditions
ConditionsYield
With potassium carbonate In water for 2h; Reflux;100%
61-90-5

L-leucine

60702-69-4

2-chloro-4-fluorobenzonitrile

N-(3-chloro-4-cyanophenyl)-L-leucine

Conditions
ConditionsYield
With caesium carbonate at 90℃; for 12h;100%
61-90-5

L-leucine

17720-18-2

1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate (S)-2-ammonio-4-methylpentanoate

Conditions
ConditionsYield
In water pH=5.61; Cooling with ice;100%
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    61-90-5

    Food grade L-Leucine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 15.0-15.0/Kilogram

    Quick Details Place of Origin: Shaanxi, China Type: Anti-Allergic Agents, Immune Function Agents, Vitamins, Amino Acids and Coenzymes CAS No.: 61-90

    DB Biotech co., ltd is a global and professional supplier for plant extracts and functional ingredients, the company is based in XI’an city, which is famous city for the producttio

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  • High Quality China supply L-Leucine CAS:61-90-5 CAS NO.61-90-5

  • Casno:

    61-90-5

    High Quality China supply L-Leucine CAS:61-90-5 CAS NO.61-90-5

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  • L-Leucine

  • Casno:

    61-90-5

    L-Leucine

    Min.Order: 25 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    L-Leucine can be used in the food industry in nutrition supplements, added to food, It can improve the nutritional value of protein, so that adequate food nutrients more reasonable.and glucose in a flavor enhancer in food processing role. L-Leuc

    Qingdao Wanyuan Mountain Biological Technology Co., Ltd. was established in 2004.Our company has passed the ISO9001 international quality system certification. After years of devel

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    Business Type:Manufacturers

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    Greenutra Resource is committed to the natural ingredients, formulation and application in the field of R&D, production and sales as the “one-step” natural product solution provide

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    Address:No. 7-1-1802, Huizhi Garden,Ocean Square,Dalian, 116033, China

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    Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

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    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

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    Product Name: L-Leucine Synonyms: (s)-2-amino-4-methylvalericacid;1-Leucine;2-Amino-4-methylpentanoic acid;2-amino-4-methylpentanoicacid;2-amino-4-me… Founded in 2014, as a professional international pharmaceutical corporation, headquarter

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    61-90-5

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    Products name Leucine Introduction As an essential amino acid, leucine is not synthesized in animals, hence it must be ingested, usually as a component of proteins. It is synthesized in plants and microorganisms via se

    Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-029-86712509

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    What's our company advantages 1. Government support guarantees good company credibility and finance safe. 2. Finer chem is confident at the quality of the products, and would like to supply free sample to our customers. 3. Factory locates in n

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    1. Who are we We are based in Shaanxi, China, start from 2018,sell to North America(00.00%), Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%), Eastern Europe(00.00%). There are total about 11-50 people in our office. 2. How can

    Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of S

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    Factory supply high quality L-Leucine,61-90-5 TAIHO Unique Advantages: 1.We're factory 2.Free samples available 3.Commodity inspection can be done 4.ISO9001,Kosher certifications 5.10 years experiences Appearance:powder Storage:Store in cool &dr

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    Business Type:Manufacturers

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    Address:No. 49 taifeng Road,Qianjiang City,Hubei,China

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    61-90-5

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    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

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  • High Quality Amino Acid CAS No.61-90-5 L-Leucine 99% powder

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    61-90-5

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    High Quality Amino Acid CAS No.61-90-5 L-Leucine 99% powder Xi'an Quanao Biotech Co., Ltd. is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, h

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    Business Type:Manufacturers

    Tel:+86-29-86719484

    Address:B-1604,Juncheng Guoji, Taiyuan Road, Weiyang distirct

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    61-90-5

    L-Leucine

    Min.Order: 1 Gram

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    20-year experience in Phytochemicals Each product has passed very strict tests (NMR\MS\HPLC) Agents in 13 countries Certified by ISO 9001:2008 quality management system Leader Supplier of Botanical Reference Materials in China

    Located in Zhangjiang High-tech Park , Shanghai , the building of Shanghai Tauto Biotech Co., Ltd. occupies a 2-hectare floor space and boasts a building area of 20,000 square mete

  •  shanghai Tauto Biotech Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-21-51320588 ext. 8025

    Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA

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  • Casno:

    61-90-5

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    Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aro

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     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

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  • Factory Price L Leucine Powder L-Leucine

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    61-90-5

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    Min.Order: 1 Kilogram

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    1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery by well-reputed shipping lines. 4.Trial order is available for testing after samples. 5.We will inform you all the information at every stage in ad

    Shaanxi greenyo biotech co., ltd is one specialized company which engaged in the naturalplant extracts, pharmaceutical intermediates, chemical raw materials research and developmen

  •  Shaanxi Greenyo Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-29-81772657

    Address:Gaoxin 4th road, High-tech zone,

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  • L-LEUCINE

  • Casno:

    61-90-5

    L-LEUCINE

    Min.Order: 25 Kilogram

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    1. GMP AVALIABLE ; 2. IN STOCK 3. FAST REPLY QUALIFED ; EFFICIENCY; RESPONSIBLE Package:25kg/drum Application:active pharmaceutical ingredient Transportation:air/sea both ok

    HangZhou Clake Biotech CO.,LTD is located in hangzhou city ,zhejiang province,China. We are engaged in export of APIs ,excipients,food additives and finished products. With more th

  •  HANGZHOU CLAKE BIOTECH CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-571-87750367

    Address:RUIBO INTERNATIONAL ,HANGZHOU ,CHINA

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  • L-Leucine    CAS: 61-90-5

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    61-90-5

    L-Leucine CAS: 61-90-5

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    Product Name:L-Leucine Formula:C6H13NO2 Molecular Weight:131.17 CAS No.:61-90-5 EINECS:200-522-0 Density:1.036 g/cm3 Solubility:22.4 g/L (20 °C) in water Melting Point:>300 °C(lit.) Boiling Point:225.8 °C at 760 mmHg Flash P

    Welcome to Henan Sinotech! Sinotech Corporation has exceptional sourcing ability for chemicals used in Organic Fine Chemicals and APIs; Inorganic chemicals; Flame Retardants;OLED

  •  Henan Sinotech Import&Export Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-371-86181678

    Address:No. 260, Dongming Road,Jinshui District

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    61-90-5

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    ProName: L-Leucine Nutrition supplement pharmac... CasNo: 61-90-5 Molecular Formula: C6H13NO2 Appearance: crystal, powder Application: Pharmaceutical intermediates DeliveryTime: 1-2 days PackAge: as your request Port:

    Ality Group, established in 2007, is a comprehensive Chemical Supply Group with Patent Technology as its core. Ality Group operates branches in Hong Kong, Singapore and mainland Ch

  •  Ality Chemical Corporation

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    Business Type:Other

    Tel:0513-87616220

    Address:Fine chemical industry park, Nantong,Jiangsu

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    61-90-5

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    L-Leucine Quick details Chemical Name: L-Leucine CAS No.: 61-90-5 Molecular Formula: C6H13NO2 Molecular weight: 131.17 Appearance: White powder L-Leucine SPEC Items Specification

    Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and inte

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

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    61-90-5

    TIANFU-CHEM CAS:61-90-5 L-Leucine

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    L-Leucine Basic information One of the eight essential amino acids Identification Test Content Analysis toxicity Application limitation The maximum amount permitted of food additives maximum allowable resid

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

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    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

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    61-90-5

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    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

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     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+8615102730682

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

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    61-90-5

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    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

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    61-90-5

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    Business Type:Lab/Research institutions

    Tel:+86-29-86470566

    Address:Block A of Central Mansion, No.113 of Weiyang Rd, ETDZ, Xi'an, Shaanxi 710016, China

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    61-90-5

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    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-27-52345788

    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

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    61-90-5

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    DESCRIPTION Leucine (abbreviated as Leu or L) is a branched-chain α-amino acid with the chemical formula HO2CCH(NH2)CH2CH(CH3)2. Leucine is classified as a hydrophobic amino acid due to its aliphatic isobutyl side chain. It is encoded by

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    Business Type:Trading Company

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    61-90-5

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18871490254

    Address:High-tech Industrial Park,Tianmen city,Hubei province.

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    61-90-5

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    L-Leucine[CAS:61-90-5] Name L-Leucine Synonyms L-2-Amino-4-methylpentanoic acid; (S)-2-Amino-4-methylpentanoic acid; L-Leu HANGZHOU THINK CHEMICAL CO., LTD. (THINKCH

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     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-571-89986307/81956191/81956084/81956192

    Address:Room 719 Building D Meidu Plaza 789 Moganshan Road

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    61-90-5

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    Our advantages 1, Rich Experience in produce----We have 26 years experiences in chemical products and 6years experiences in Pharmaceutical Intermediate products and APIS. 2, Competitive price ---We have the competitive price owing to low

    Welcome to Hebei Bosang International Trade Co.,Ltd. Hebei Bosang International Trade Co.,Ltd. specializes in exporting high quality Pharmaceutical intermediates,Pharmaceutical

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15630118152

    Address:Wanda Plaza Commercial Complex, 123 Huaian East Road, Yuhua District, Shijiazhuang City, Hebei Province, China

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    61-90-5

    L-Leucine

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    1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: L-Leucine Molecular Structure: Formula: C6H13NO2 Molecular Weight : 131.17 Synonyms: (s)-2-amino-4-methylvalericacid;1-Leucine;2-Amino-4-methylpentanoicaci

    Hubei Hanways Pharmchem Co.,Limited is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. Now we

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    Business Type:Trading Company

    Tel:+86-18502787239(whatsapp)

    Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China

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    61-90-5

    L-Leucine 61-90-5

    Min.Order: 1 Kilogram

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  • L-Leucine/CAS:	61-90-5

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    Name: L-leucine Molecular Formula: C6H13NO2 CAS Number: 61-90-5 Package: According to the customer's request Export Port: Wuhan, Shanghai, Shenzhen, Guangzhou, etc, Purity: 99% min Storage condition: Refrigerator store (within the

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Consensus Reports

Reported in EPA TSCA Inventory.

Specification

1. Introduction of L-Leucine

L-Leucine, with the IUPAC Nameof (2S)-2-amino-4-methylpentanoic acid, is one kind of white crystalline powder. For being stable in the normal condition, it si sensitive to moisture and light, and this chemical is incompatible with strong oxidising agents. Besides, it belongs to the Product Categories which include Food and Feed Additive; Amino Acid Derivatives; Leucine [Leu, L]; Amino Acids; Amino Acids and Derivatives; alpha-Amino Acids; Biochemistry; Nutritional Supplements; L-Amino Acids; Amino Acids.

2. Properties of L-Leucine

L-Leucine has the following property datas: (1)Index of Refraction: 1.462; (2)Molar Refractivity: 34.86 cm3; (3)Molar Volume: 126.6 cm3; (4)Polarizability: 13.82×10-24cm3; (5)Surface Tension: 39 dyne/cm; (6)Density: 1.035 g/cm3; (7)Flash Point: 90.3 °C; (8)Enthalpy of Vaporization: 50.93 kJ/mol; (9)Melting Point: >300 °C(lit.); (10)Boiling Point: 225.8 °C at 760 mmHg; (11)Vapour Pressure: 0.0309 mmHg at 25°C; (12)Solubility: 1 M HCl: 50 mg/mL; (13)Water Solubility: 22.4 g/L (20 C).

3. Structure Descriptors of L-Leucine

You could convert the following datas into the molecular structure:
(1). InChI: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 
(2). InChIKey: InChIKey=ROHFNLRQFUQHCH-YFKPBYRVSA-N 
(3). Smiles: C([C@@H](C(O)=O)N)C(C)C

4. Toxicity of L-Leucine

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LDLo subcutaneous 2620mg/kg (2620mg/kg)   Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 40, Pg. 313, 1898.
rat LD50 intraperitoneal 5379mg/kg (5379mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Archives of Biochemistry and Biophysics. Vol. 58, Pg. 253, 1955.
 

5. Safety Information of L-Leucine

Safety Statements of L-Leucine (CAS NO.61-90-5): 24/25 
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: OH2850000
HS Code: 29224995
Moderately toxic by subcutaneous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

6. Use and Preparation of L-Leucine

L-Leucine is used for pharmaceutical raw materials and food additives. As a food additive, it has E number E641 and is classified as a flavour enhancer.