Tetrahedron Letters p. 2725 - 2728 (1992)
Update date:2022-08-04
Topics:
Amoroso
Cardillo
Tomasini
The highly diastereoselective alkylation of 6-methylperihydropyrimidin-4-ones 1 and 2 has been reported. The corresponding lithium enolates have been alkylated under a variety of conditions with good trans selectivity and all the reaction products have been easily separated and characterised.
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