The total synthesis of swinholide A. Part 1 : A stereocontrolled synthesis of a C19-C32 segment

DOI: 10.1016/0040-4020(95)00546-K

Source and publish data:

Tetrahedron p. 9393 - 9412 (1995)

Update date:2022-08-04

Topics:

Authors:

Paterson, Ian

Cumming, John G.

Ward, Richard A.

Lamboley, Serge

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00546-K

The C₁₉-C₃₂ segment 10 of swinholide A was prepared in 15 steps (8% yield, 82% ds) from (±)-16. Key steps include (i) the Sharpless epoxidation, 16 → 17, (ii) the acetal allylation, 15 → 23, (iii) the anti aldol addition, 13 + 14 → 1

Full text of DOI:10.1016/0040-4020(95)00546-K

Products guided by the article

Product name:(E)-(2S,3S,4R,5R)-1-benzyloxy-2,4,6-trimethyl-8-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-oct-6-en-3,5-diol

Cas No:142144-28-3

R&D Labs maybe for 142144-28-3

Alchemy industrial limited

Contact:+86-18200374913

Address:Hongmei Road, No. 99
Chengdu CSH Pharmaceutical Co.,ltd

Contact:+86-(28)-85321971

Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
MedicalChem(Yancheng)Manuf.Co.,Ltd.

Contact:+86-515-84383366

Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
Quhua Zhongxing Refrigeration Technology Co.,Ltd.

Contact:+86-5708886618

Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou

Relevant to this article

Catalytic asymmetric [4 + 2] cycloadditions and Hosomi-Sakurai reactions of α-alkylidene β-keto imides

Doi:10.1021/ol303381c
(2013)
Robust phosphorescent platinum(ii) complexes with tetradentate O ^∧N^∧C^∧N ligands: High efficiency OLEDs with excellent efficiency stability

Doi:10.1039/c2cc37862k
(2013)
Design, synthesis, and structure-activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

Doi:10.1016/j.bmc.2012.11.041
(2013)
First stereoselective total synthesis of pectinolide C and total synthesis of pectinolide A

Doi:10.1016/j.tetlet.2012.12.039
(2013)
O-xylylene protecting group in carbohydrate chemistry: Application to the regioselective protection of a single vic-diol segment in cyclodextrins

Doi:10.1021/jo302178f
(2013)
Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4

Doi:10.1016/j.bmc.2017.12.023
(2018)

Article Doi