A formal total synthesis of PGA2 using the directed Pauson-Khand reaction

DOI: 10.1016/0040-4039(92)88036-5

Source and publish data:

Tetrahedron Letters p. 151 - 152 (1992)

Update date:2022-07-30

Topics: Retrosynthetic analysis Purification and characterization Final steps Synthesis of the Precursor

Authors:

Krafft, Marie E.

Wright, Colin

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Article abstract of DOI:10.1016/0040-4039(92)88036-5

3,3a,4,6a-Tetrahydro-2-methoxy-2H-cyclopenta[b]furan-4-methanol 1, a key intermediate in the synthesis of PGA₂ 2, was prepared via the first example of the use of the directed Pauson-Khand reaction in a natural product synthesis.

Full text of DOI:10.1016/0040-4039(92)88036-5

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