Channel-Type Molecular Structures Part 2 Synthesis of Bouquet-Shaped Molecules Based on a β-Cyclodextrin Core

Article abstract of DOI:10.1002/hlca.19920750315

A new series of channel-type molecules presenting the features of potential transmembrane structures is described.They result from the grafting of amphiphilic side chains on a β-cyclodextrin derivative 3 that constitutes the organizing core.They belong to the 'bouquet' family (B).Compounds bearing poly(oxyethylene) side chains, B^O_CD 16 and 17, and their polymethylene analogues B^C_CD 18 and 19, were synthesized.The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes.