Journal of Organic Chemistry p. 5150 - 5154 (1992)
Update date:2022-08-02
Topics:
Burkhart, Joseph P.
Huber, Edward W.
Laskovics, F. Mark
Peet, Norton P.
The syntheses of 2,19-(methyleneoxy)androst-4-ene-3,17-dione (4a), a potent, time-dependent inhibitor of human placental aromatase, and its thio (4b), amino (5), and methylene (14) analogs are descibed.The key step in the construction of 4a, 4b, and 5 is
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