6-Alkyl-12-formylindolo[2,1-a]isoquinolines. Syntheses, estrogen receptor binding affinities, and stereospecific cytostatic activity

DOI: 10.1021/jm00097a011

Source and publish data:

Journal of Medicinal Chemistry p. 3537 - 3547 (1992)

Update date:2022-08-05

Topics:

Authors:

Polossek

Ambros Ambros

Von Angerer

Brandl Brandl

Mannschreck

Von Angerer

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00097a011

A number of 6-alkyl-12-formyl-5,6-dihydroindolo[2,1-a]isoquinolines were synthesized by the Bischler-Napieralski reaction from the respective 1-alkyl- 2-(3-methoxyphenyl)ethylamines and bromo-substituted (methoxyphenyl)acetic acid chlorides followed by a

Full text of DOI:10.1021/jm00097a011

Products guided by the article

Product name:2-(3-Bromo-4-methoxy-phenyl)-N-[1-(3-methoxy-benzyl)-butyl]-acetamide

Cas No:143398-57-6

R&D Labs maybe for 143398-57-6

Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing
Shanghai Science Peptide Biological Technology Co.,ltd

website:http://www.scipeptide.com

Contact:+86-21-51099675

Address:No.8 Changyang Rd
Wuhan Kemi-Works Chemical Co., Ltd

website:http://www.kemiworks.com

Contact:86-27-85736489

Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
Shanghai Apeptide Co., Ltd.

website:http://www.apeptides.com/en/

Contact:+86-21-60871011

Address:No. 80 Chuanshan Shuyuan Steet,Pudong,Shanghai
Fusilin chemical science & technology co., ltd.

Contact:532-80698166/86057573, +86-400-669-7885

Address:School of Material Science & Engineering, Shandong Uinversity of Science & Technology, Huangdao Zone, Qindao, Shandong

Relevant to this article

Catalytic enantioselective cyclopropanation with bis(halomethyl) zinc reagents. II. The effect of promoter structure on selectivity

Doi:10.1016/0040-4039(95)00259-F
(1995)
Regiospecific synthesis of arenofurans via cascade reactions of arenols with Morita-Baylis-Hillman acetates of nitroalkenes and total synthesis of isoparvifuran

Doi:10.1016/j.tet.2013.04.023
(2013)
Preparation of S14161 and its analogues and the discovery of 6-bromo-8-ethoxy-3-nitro-2H-chromene as a more potent antitumor agent in vitro

Doi:10.1016/j.bmcl.2013.03.097
(2013)
Regioselective cleavage of unstrained C-C bond and C-H bond: Palladium-copper catalyzed deacetophenonylative arylation of coumarin derivatives

Doi:10.1002/adsc.201200539
(2012)
Cesium carbonate-promoted hydroamidation of alkynes: Enamides, indoles and the effect of iron(III) chloride

Doi:10.1002/adsc.201200430
(2012)
Silver-Mediated [3 + 2] Cycloaddition of Azomethine Ylides with Trifluoroacetimidoyl Chlorides for the Synthesis of 5-(Trifluoromethyl)imidazoles

Doi:10.1021/acs.joc.1c00131
(2021)

Article Doi