Thromboxane Receptor Antagonism Combined with Thromboxane Synthase Inhibition. 5. Synthesis and Evaluation of Enantiomers of 8-amino>-4-(3-pyridinylalkyl)octanoic Acid

DOI: 10.1021/jm00054a003

Source and publish data:

Journal of Medicinal Chemistry p. 205 - 210 (1993)

Update date:2022-09-26

Topics:

Authors:

Bhagwat, Shripad S.

Gude, Candido

Cohen, David S.

Dotson, Ron

Mathis, Janice

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00054a003

The enantiomers of 8-<<(4-chlorophenyl)sulfonyl>amino>-4-(3-pyridinylpropyl)octanoic acid (1) and its pyridinyl ether analog (2) were synthesized using the highly diastereoselective method of alkylation of acyloxazolidinone.These enantiomerically pure com

Full text of DOI:10.1021/jm00054a003

Products guided by the article

Product name:(2'R,4S)-4-benzyl-3-<2'-allyl-6'-(benzyloxy)hexanoyl>oxazolidin-2-one

Cas No:143761-24-4

R&D Labs maybe for 143761-24-4

Shanghai Haoyuan Chemexpress Co., Ltd.

website:https://www.chemexpress.com/

Contact:86-21-58950125

Address:No.3 Building, No.1999, Zhangheng Road, ZhangjiangHighTech Park, Shanghai, P.R.China,201203
zhuzhou zhongle chemical co. ltd.

Contact:+86-0731 28228409

Address:Zhuzhou, Hunan, China
Shanghai Demand Chemical Co., ltd，China

Contact:86-021-55237578/55239122

Address:Room 3H, No.578, Yingkou Road, Yangpu District, Shanghai, China
Shanghai Dano Pharmaceutical Co.,Ld.(expird)

Contact:+86-592-6266840

Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China
Suzhou Howsine Biological Technology Co.,Ltd(expird)

website:http://www.howsine.com

Contact:86-512-67262751

Address:No 3,Weihua Road ,Suzhou Industrial Park ,Jiangsu ,China.

Relevant to this article

Synthesis of structure and function diverse α-D-diazoacetates, α-D-diazoacetamides, α-D-diazoketones, and the antibiotic α-D-azaserine

Doi:10.1055/s-0032-1318136
(2013)
Conformational Studies by Dynamic NMR. 97.¹ Structure, Conformation, Stereodynamics and Enantioseparation of Aryl Substituted Norbornanes

Doi:10.1021/jo035411n
(2004)
Chromium-thiophene-salen-based polymers for heterogeneous asymmetric hetero-Diels-Alder reactions

Doi:10.1002/ejoc.200701218
(2008)
Neuroleptics from the 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole Series. 3. Carboxamidoalkyl Derivatives

Doi:10.1021/jm00160a053
(1986)
Selective β-hydroxyethylation at the N-1 position of a pyrazolone: Synthesis of benzyl 1-(β-hydroxyethyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro- 1H-pyrazole-4-carboxylate

Doi:10.1055/s-2008-1042923
(2008)
Tetrasubstituted Phthalocyanines with Benzoic Acids Moieties

Doi:10.1134/S1070363219060264
(2019)

Article Doi