Thromboxane Receptor Antagonism Combined with Thromboxane Synthase Inhibition. 5. Synthesis and Evaluation of Enantiomers of 8-amino>-4-(3-pyridinylalkyl)octanoic Acid

DOI: 10.1021/jm00054a003

Source and publish data:

Journal of Medicinal Chemistry p. 205 - 210 (1993)

Update date:2022-09-26

Topics:

Authors:

Bhagwat, Shripad S.

Gude, Candido

Cohen, David S.

Dotson, Ron

Mathis, Janice

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00054a003

The enantiomers of 8-<<(4-chlorophenyl)sulfonyl>amino>-4-(3-pyridinylpropyl)octanoic acid (1) and its pyridinyl ether analog (2) were synthesized using the highly diastereoselective method of alkylation of acyloxazolidinone.These enantiomerically pure com

Full text of DOI:10.1021/jm00054a003

Products guided by the article

Product name:(2'R,4S)-4-benzyl-3-<2'-allyl-6'-(benzyloxy)hexanoyl>oxazolidin-2-one

Cas No:143761-24-4

R&D Labs maybe for 143761-24-4

Meryer (Shanghai) Chemical Technology Co., Ltd.

website:http://www.meryer.com/cn/index/

Contact:+86-755-86170518

Address:Minhang,Shanghai, China
Beijing Tianjia Chemical Science & Technology Co.,Ltd

Contact:86-0550-2392698

Address:No.388, Shiliang Road (East),
Shanxi Sanwei Group Co.,Ltd

Contact:0086-357-6662688

Address:Zhaocheng town, Hongtong County, Linfen City, Shanxi Province
Hefei Highzone Fine Chemical S&T CO.,LTD

Contact:86-0551-63663560

Address:room 1801 NO. 24 Shuguang RD.
Shanghai Kangxin Chemical Co., Ltd

Contact:+86 21 60717227

Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai

Relevant to this article

Synthesis of structure and function diverse α-D-diazoacetates, α-D-diazoacetamides, α-D-diazoketones, and the antibiotic α-D-azaserine

Doi:10.1055/s-0032-1318136
(2013)
Conformational Studies by Dynamic NMR. 97.¹ Structure, Conformation, Stereodynamics and Enantioseparation of Aryl Substituted Norbornanes

Doi:10.1021/jo035411n
(2004)
Chromium-thiophene-salen-based polymers for heterogeneous asymmetric hetero-Diels-Alder reactions

Doi:10.1002/ejoc.200701218
(2008)
Neuroleptics from the 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole Series. 3. Carboxamidoalkyl Derivatives

Doi:10.1021/jm00160a053
(1986)
Selective β-hydroxyethylation at the N-1 position of a pyrazolone: Synthesis of benzyl 1-(β-hydroxyethyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro- 1H-pyrazole-4-carboxylate

Doi:10.1055/s-2008-1042923
(2008)
Tetrasubstituted Phthalocyanines with Benzoic Acids Moieties

Doi:10.1134/S1070363219060264
(2019)

Article Doi